Juan Manuel Castellote

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A multiple case study was conducted in order to assess three leading theories of developmental dyslexia: (i) the phonological theory, (ii) the magnocellular (auditory and visual) theory and (iii) the cerebellar theory. Sixteen dyslexic and 16 control university students were administered a full battery of psychometric, phonological, auditory, visual and(More)
BACKGROUND Incidence studies of spinal cord injury (SCI) are important for health-care planning and epidemiological research. This review gives a quantitative update on SCI epidemiology worldwide through a statistical evaluation of incidence rates. METHODS A systematic review was conducted. For each study, the crude rate ratio was calculated and, when(More)
A startling auditory stimulus delivered during preparation for execution of a ballistic movement in a simple reaction time task experiment induces two effects: a startle response and a reaction time shortening (the StartReact effect). We investigated whether prepulse inhibition of the startle response is effective in suppressing either one of these effects(More)
Spinal cord injury (SCI) leading to neurological deficits produces long-term effects that persist over a lifetime. Survival analysis of patients with SCI, at individual and population level, is important for public health management and the assessment of treatment achievements. The current study evaluated survival following traumatic and non-traumatic SCI(More)
The size of the response to a startling auditory stimulus (SAS) may reflect the excitability of the reticulospinal tract. In this study, we examined whether there was any excitability change in the reticulospinal tract during preparation for execution of two types of choice reaction time task: a forced choice reaction time task (fCRT) and a Go/no-Go task(More)
The control of eye movements depends in part on subcortical motor centres. Gaze is often directed towards salient visual stimuli of our environment with no conscious voluntary commands. To further understand to what extent preprogrammed eye movements can be triggered subcortically, we carried out a study in normal volunteers to examine the effects of a(More)
In preparation for performing task specific ballistic movements, subjects may choose among different possibilities for setting up their motor apparatus, ranging from quiet resting to different types of muscle activation. In the study presented here, we investigated whether differences in the motor set modify either the reaction time or the kinematic(More)
An experimental mononeuropathy was produced in rats by unilateral loose ligation of the sciatic nerve, with a contralateral sham surgery. Repeated bilateral sensory testing was performed over time to investigate any threshold differences between the loose ligature side and the contralateral control side. A prolonged reduction in the mean withdrawal(More)
The execution of a ballistic movement within a reaction time task paradigm is significantly speeded up when an unexpected startling auditory stimulus (SAS) is delivered together with the imperative signal. Using Libet’s clock, we investigated whether acceleration involves also the subjective appraisal of the time of task execution. In trials containing the(More)
Corticosteroids are probably an effective treatment for some types of neuropathic pain and complex regional pain syndromes. This study examined the effects of systemic methylprednisolone (MP) on acute nociception and on pain behavior and hyperalgesia in normal and neuropathic rats. There was no dose-response to intraperitoneal MP (up to 12 mg/kg) for(More)