Juan M.J. Ramos

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BACKGROUND Breast carcinoma is the most common cancer and the second leading cause of cancer-related deaths among women. The disease represents approximately 31% of all cancers in Puerto Rican women. Several DNA repair pathways are involved in preventing carcinogenesis. The current study evaluated the hypothesis that a reduced DNA repair capacity (DRC) is a(More)
BACKGROUND UV radiation is a risk factor for nonmelanoma skin cancer (NMSC). The relation between DNA damage and oncogenesis suggests that diminished DNA repair capacity (DRC) is involved in tumorigenesis. OBJECTIVE The purpose of this study was to test the hypothesis that a low DRC is a susceptibility factor for the development of NMSC in Puerto Rico. (More)
Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), known as nonmelanoma skin cancer (NMSC), are the most common cancers worldwide. Although many factors are involved in the pathogenesis of NMSC, UV radiation is an important risk factor. A fundamental question in skin cancer research is whether varying doses of total UV radiation influence key(More)
Using a four-arm plus-shaped maze, rats with neurotoxic lesions in the dorsal hippocampus were trained in a spatial reference memory task in which both the extramaze constellation of stimuli and an intramaze landmark (a piece of sandpaper covering the ̄oor of the goal) indicated the location of the goal arm. After reaching criterion, animals were given two(More)
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