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Journals and Conferences
OBJECTIVE To compare the effectiveness of two regimens of albendazole therapy for neurocysticercosis. DESIGN Randomized, double-blind clinical trial. SETTINGS Patients admitted to neurologic wards in Lima, Peru. PATIENTS Adult patients with active neurocysticercosis demonstrated by CT and Western blot (immunoblot). INTERVENTION One week (n = 25)… (More)
Three of 6 patients with spastic paraparesis in Lima, Peru, were found to have antibodies to human T-lymphotropic virus type I (HTLV-I). Blood and cerebrospinal fluid antibodies were confirmed by Western blot analysis. Multilobulated lymphocytes in blood and cerebrospinal fluid of the index case stained with monoclonal antibodies for T-helper cells and for… (More)
BACKGROUND Mutations in PARK2 result in autosomal recessive young onset Parkinson's disease (YOPD). Although there have been a number of reports on the clinical characteristics of PARK2-related PD, there is limited information available on the associated neuropathologic changes. DESIGN We describe the clinical and pathological characteristics of a… (More)
Since 1970, 91 patients with Huntington's chorea have been identified in Peru, the majority of them, 42 cases, living in Cañete, a valley 140 km from Lima. The precise origin of the disease is unknown, but these patients are mostly half-bred from a mixture of White and Indian rather than from a mixture of Chinese, Japanese or Black.
One case of ataxic, pyramidal and demential syndrome associated with retinitis pigmentosa occurred in a family with Huntington's disease (36 patients among 7 generations). The disease started at 15 years of age. Ataxia was transiently attenuated by isoniazid. The patient died of the disease at 26 years of age.