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Anthropogenic and environmental factors associated with high prevalence of mcr-1 carriage in humans across China
TLDR
The high prevalence of MCRPEC in the community poses a substantial risk for colistin usage in clinical practice and suggests the need for intestinal screening of mCR-1 carriers in intensive care units in Chinese hospitals, and suggests that aquaculture is a significant reservoir of mcr-1.
First Report of Klebsiella oxytoca Strain Simultaneously Producing NDM-1, IMP-4, and KPC-2 Carbapenemases
TLDR
It is reported for the first time, to the authors' knowledge, coproducing NDM-1, KPC-2, and IMP-4 carbapenemases on a K. oxytoca isolate.
Detection and dissemination of the colistin resistance gene, mcr‐1, from isolates and faecal samples in China
TLDR
The data demonstrate that the mcr‐1 gene is highly prevalent in human and animal populations in China, and suggests that active surveillance of the m cristin resistance gene is imperative in curtailing its spread.
pSY153-MDR, a p12969-DIM-related mega plasmid carrying blaIMP-45 and armA, from clinical Pseudomonas putida.
TLDR
Deep insight is provided into the evolutionary history of SY153, especially in regard to how it became extensively drug-resistant, and fifteen non-redundant resistance markers were identified to be involved in resistance to at least eight distinct classes of antibiotics.
pO157_Sal, a Novel Conjugative Plasmid Detected in Outbreak Isolates of Escherichia coli O157:H7
TLDR
A novel 38-kb conjugative plasmid, pO157_Sal, was identified and sequenced from an Escherichia coli O157:H7 outbreak-associated Chinese isolate that shares high similarity with a plasmids in Salmonella enterica serovar Agona.
Multiple Cross Displacement Amplification Coupled with Gold Nanoparticles-Based Lateral Flow Biosensor for Detection of the Mobilized Colistin Resistance Gene mcr-1
TLDR
A multiple cross displacement amplification (MCDA) coupled with the detection of amplified products by gold nanoparticles-based lateral flow biosensor (LFB) assay was established to identify the mcr-1 gene with simpleness, rapidity, specificity and sensitivity, suitable for the surveillance of m cristin resistance in clinic and livestock industry.
Saccharicrinis carchari sp. nov., isolated from a shark, and emended descriptions of the genus Saccharicrinis and Saccharicrinis fermentans.
TLDR
A phylogenetic tree, based on 16S rRNA gene sequences, showed that strain SS12(T) and Saccharicrinis fermentans DSM 9555(T%) formed a distinct cluster within the family Marinilabiliaceae.
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