Juan-José López

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The production of biomass and lovastatin by spore-initiated submerged fermentations of Aspergillus terreus ATCC 20542 was shown to depend on the age of the spores used for inoculation. Cultures started from older spores produced significantly higher titers of lovastatin. For example, the lovastatin titer increased by 52% when the spore age at inoculation(More)
The present paper makes a comparative analysis of the outdoor culture of H. pluvialis in a tubular photobioreactor and a bubble column. Both reactors had the same volume and were operated in the same way, thus allowing the influence of the reactor design to be analyzed. Due to the large changes in cell morphology and biochemical composition of H. pluvialis(More)
BACKGROUND Chemotherapy is widely used in colorectal cancer that has relapsed or failed to respond to first-line treatment. OBJECTIVES To determine the efficacy of second-line chemotherapy for the treatment of advanced colorectal cancer. SEARCH STRATEGY We performed electronic searches in the following databases: MEDLINE (via PubMed; 1964-September(More)
  • J Lopez
  • 1976
Extensive review of the literature reveals that the diagnostic benefits of xeroradiography in medicine are rapidly being recognized. It is viewed with particular interest by clinicians managing neoplasms of the laryngopharyngeal, mammary, and joint regions. Xeroradiography is a definite aid in cephalometric analysis. Examples of use have been presented. The(More)