Juan Ignacio López-Gastón

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INTRODUCTION Patients with stroke associated with non-valvular atrial fibrillation (NVAF) are a specific group, and their disease has a considerable social and economic impact. The primary objective of the CONOCES study, the protocol of which is presented here, is to compare the costs of stroke in NVAF patients to those of patients without NVAF in Spanish(More)
INTRODUCTION The intracranial hypotension syndrome is characterized by a cerebrospinal fluid (CSF) pressure of less than 60 mmH2O and presents as postural hypotension which is often accompanied by nausea, vomiting, cervicalgia and some degree of neck rigidity. It is considered to be spontaneous when there is no known precipitating factor. It is believed(More)
Genetic human prion diseases are autosomal dominant disorders associated with different mutations in the PRNP gene that are manifested as distinct clinical phenotypes. Here, we report a new pathogenic missense mutation (c.[643A>G], p.[I215V]) in the PRNP gene associated with three pathologically confirmed cases: two of Creutzfeldt–Jakob disease (CJD) and(More)
INTRODUCTION Management of cerebral vascular pathologies by means of clinical pathways allows us to make cost effective use of resources, to enhance health care quality and to obtain a greater degree of satisfaction in patients. AIMS To assess the efficiency of applying a clinical pathway designed for the treatment of transient ischemic attacks (TIA) by(More)
INTRODUCTION Neurological pathology as the initial form of sarcoidosis is exceptional. Neurosarcoidosis represents 5% of all cases. Central nervous system involvement is more frequent in the acute forms of this illness, whilst myositis and peripheral neuropathy are more common in chronic sarcoidosis. CLINICAL CASE A 60 year old woman presented with(More)
INTRODUCTION Aneurysms of the atrial septum (AAS) are uncommon. They have been considered to be related to embolic phenomena. They are usually associated with other cardiac anomalies, especially persistence of the formen ovale. PATIENTS AND METHODS We studied six patients diagnosed during a period of 24 months as having ischemic ictus and AAS. They were(More)
INTRODUCTION Quality of care involves meeting the needs and expectations of patients with the lowest consumption of resources and in accordance with scientific knowledge. In this context it is important to know if the changes in medical care procedures based on scientific and technical aspects of the quality positively impacts both efficiency measures and(More)
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