Juan F. Guerrero

Learn More
Because of its electrophysiological effects, hypothermia can influence the mechanisms that intervene in the sustaining of ventricular fibrillation. We hypothesized that a rapid and profound reduction of myocardial temperature impedes the maintenance of ventricular fibrillation, leading to termination of the arrhythmia. High-resolution epicardial mapping(More)
INTRODUCTION We hypothesize that local modifications in electrophysiological properties, when confined to zones of limited extent, induce few changes in the global activation process during ventricular fibrillation (VF). To test this hypothesis, we produced local electrophysiological modifications by stretching a circumscribed zone of the left ventricular(More)
INTRODUCTION AND OBJECTIVES An experimental model is used to analyze the characteristics of ventricular fibrillation in situations of variable complexity, establishing relationships among the data produced by different methods for analyzing the arrhythmia. METHODS In 27 isolated rabbit heart preparations studied under the action of drugs (propranolol and(More)
INTRODUCTION AND OBJECTIVES The analysis of frequency variability during ventricular fibrillation has yielded inconsistent results. We used an experimental model of ventricular fibrillation, with a short timescale, to analyze variations in frequency and their associated spatial distribution. METHODS Epicardial recordings of ventricular fibrillation were(More)
INTRODUCTION AND OBJECTIVES Although electro- physiological databases contain information about changes in the time domain in lesions produced by radiofrequency ablation, very few data on changes in the frequency domain are available. The aim of this study was to investigate changes in the spectral characteristics of ventricular fibrillation in zones with(More)
INTRODUCTION AND OBJECTIVES The aim of this study was to examine the hypothesis that the recording mode (i.e., unipolar or bipolar) affects the information obtained using spectral analysis techniques during ventricular fibrillation by carrying out an experiment using epicardial electrodes. METHODS Recordings of ventricular fibrillation were obtained in 29(More)
KEY POINTS The nucleus incertus is a key node of the brainstem circuitry involved in hippocampal theta rhythmicity. Synchronisation exists between the nucleus incertus and hippocampal activities during theta periods. By the Granger causality analysis, we demonstrated a directional information flow between theta rhythmical neurons in the nucleus incertus and(More)
INTRODUCTION AND OBJECTIVES An analysis was made of the effects of a radiofrequency-induced linear lesion during ventricular fibrillation and the capacity to capture myocardium through high-frequency pacing. METHODS Using multiple epicardial electrodes, ventricular fibrillation was recorded in 22 isolated perfused rabbit hearts, analyzing the activation(More)
This work presents the application of machine learning techniques to analyse the influence of physical exercise in the physiological properties of the heart, during ventricular fibrillation. To this end, different kinds of classifiers (linear and neural models) are used to classify between trained and sedentary rabbit hearts. The use of those classifiers in(More)
This study analyses the modifications produced by physical exercise in cardiac mapping recordings during Ventricular Fibrillation (VF), compared to the ones produced by Glibenclamide. Three groups of rabbits were used. Gl: control (sedentary rabbits), G2: trained (rabbits submitted to a running program) and G3: drugged (sedentary rabbits treated with(More)