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- Begoña Echeverría, Juan Etxebarria, +5 authors Niels-Christian Reichardt
- Analytical chemistry
- 2015
Methods for the absolute quantification of glycans are needed in glycoproteomics, during development and production of biopharmaceuticals and for the clinical analysis of glycan disease markers. Here… (More)
An effective chemoenzymatic strategy is reported that has allowed the construction, for the first time, of a focused microarray of synthetic N-glycans. Based on modular approaches, a variety of… (More)
- Juan Etxebarria, Javier Escayola Calvo, Manuel Martín-Lomas, Niels-Christian Reichardt
- ACS chemical biology
- 2012
By combining electrophoretic protein separation with lectin-array-based glycan profiling into a single experiment, we have developed a high-throughput method for the rapid analysis of protein… (More)
- Juan Etxebarria, Niels-Christian Reichardt
- Biochimica et biophysica acta
- 2016
BACKGROUND
Many treatment options especially for cancer show a low efficacy for the majority of patients demanding improved biomarker panels for patient stratification. Changes in glycosylation are a… (More)
- Juan Etxebarria, Sonia Serna, Ana Beloqui, Manuel Martín-Lomas, Niels-Christian Reichardt
- Chemistry
- 2013
Glycan arrays have become the premier tool for rapidly establishing the binding or substrate specificities of lectins and carbohydrate-processing enzymes. New approaches for accelerating carbohydrate… (More)
- Juan Etxebarria, Javier Escayola Calvo, Niels-Christian Reichardt
- The Analyst
- 2014
Weathering steel has been employed for the first time to prepare sample plates for matrix-free laser desorption ionisation mass spectrometry (LDI-MS) of small molecules up to a mass range of around… (More)
The recent increase in the practice of ocular surgery and widespread use of contact lenses have led to an increase in the incidence of severe ocular infections. Inadequate management of these… (More)
- Aitziber Eleta-Lopez, Juan Etxebarria, Niels-Christian Reichardt, Radostina Georgieva, Hans Bäumler, José Luis Toca-Herrera
- Colloids and surfaces. B, Biointerfaces
- 2015
The adsorption of proteins on surfaces often results in a change of their structural behavior and consequently, a loss of bioactivity. One experimental method to study interactions on a molecular… (More)
- Victor Manuel Castillo-Acosta, Luis Miguel Ruiz Pérez, +6 authors Dolores González-Pacanowska
- PLoS pathogens
- 2016
Current treatments available for African sleeping sickness or human African trypanosomiasis (HAT) are limited, with poor efficacy and unacceptable safety profiles. Here, we report a new approach to… (More)