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Pannexin 1 Differentially Affects Neural Precursor Cell Maintenance in the Ventricular Zone and Peri-Infarct Cortex.

• Leigh E Wicki-Stordeur, Juan C Sanchez-Arias, +4 authors Leigh Anne Swayne
• The Journal of neuroscience : the official…
• 2016

UNLABELLED We demonstrated previously that Pannexin 1 (Panx1), an ion and metabolite channel, promotes the growth and proliferation of ventricular zone (VZ) neural precursor cells (NPCs) in vitro. To… (More)

Perspectives on the role of Pannexin 1 in neural precursor cell biology

• Juan C Sanchez-Arias, Leigh E Wicki-Stordeur, Leigh Anne Swayne
• Neural regeneration research
• 2016

We recently reported that targeted deletion of Pannexin 1 in neural precursor cells of the ventricular zone impairs the maintenance of these cells in healthy and stroke-injured brain. Here we frame… (More)

Upregulation of inflammatory mediators in the ventricular zone after cortical stroke.

• A. Gunton, Juan C Sanchez-Arias, Esther O Carmona-Wagner, Leigh E Wicki-Stordeur, Leigh Anne Swayne
• Proteomics. Clinical applications
• 2017

PURPOSE After cortical stroke, neural precursor cells (NPCs) in the distal ventricular zone (VZ) proliferate more rapidly and migrate toward the injured cortex. While evidence suggests this can… (More)

What Are Neural Stem Cells, and Why Are They Important?

• Leigh Anne Swayne, Juan C Sanchez-Arias, Andrew Agbay, Stephanie Michelle Willerth
• Front. Young Minds.
• 2016

1Centre for Biomedical Research, University of Victoria, Victoria, BC, Canada, 2Division of Medical Sciences, University of Victoria, Victoria, BC, Canada, 3Island Medical Program, Department of… (More)

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