Juan Antonio Márquez-Vácaro

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We set out to assess the safety and the impact on in-hospital and 90-day mortality of antibiotic de-escalation in patients admitted to the ICU with severe sepsis or septic shock. We carried out a prospective observational study enrolling patients admitted to the ICU with severe sepsis or septic shock. De-escalation was defined as discontinuation of an(More)
OBJECTIVE To determine the risk factors related to the presence of postsurgical nosocomial pneumonia (NP) in patients who had undergone cardiac surgery. DESIGN A case-control study. SETTING Postcardiac surgical intensive care unit at a university center. PATIENTS A total of 45 patients with NP and 90 control patients collected during a 4-yr period. (More)
INTRODUCTION The aims of this study were to assess the reliability of circulating cell-free DNA (cf-DNA) concentrations, compared with C-reactive protein (CRP), procalcitonin (PCT) and eosinophil count, in the diagnosis of infections in patients with systemic inflammatory response syndrome (SIRS) and their prognostic values in a cohort of critically ill(More)
OBJECTIVES To determine the attributable mortality and excess length of stay (LOS) associated with the use of inadequate empirical antimicrobial therapy in patients with sepsis at admission to the intensive care unit (ICU). METHODS A retrospective matched cohort study was performed using a prospectively collected database at a 40 bed general ICU at a(More)
To investigate prognostic factors and predictors of Acinetobacter baumannii isolation in ventilator-associated pneumonia (VAP). We specifically analyzed these issues for imipenem-resistant episodes. All episodes of VAP are prospectively included in a database. Information about risk factors was retrieved retrospectively. Eighty-one patients exhibiting(More)
OBJECTIVES A study was made of the epidemiological data of sepsis requiring admission to the ICU in patients over 65 years of age, with an evaluation of independent predictors of survival at 2 years. DESIGN A prospective cohort study was made. PATIENTS Patients meeting criteria for sepsis upon admission to the ICU. SETTING A 40-bed ICU in a tertiary(More)
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