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When two terms occur together in a document, the probability of a close relationship between them and the document itself is greater if they are in nearby positions. However , ranking functions including term proximity (TP) require larger indexes than traditional document-level indexing , which slows down query processing. Previous studies also show that(More)
Current Intrusion Detection Systems (IDS) examine all data features to detect intrusion or misuse patterns. Some of the features may be redundant or contribute little (if anything) to the detection process. The purpose of this study is to identify important input features in building an IDS that is computationally efficient and effective. This paper(More)
— To some extend, many complicated nonlinear maps are additive models of a number of linear and nonlinear terms. A single linear model or nonlinear model (i.e., a neural network model) has its limitation for approximating this class of maps. In this paper, a hybrid approach to evolve an additive tree model for a given problem is proposed. In this approach,(More)
A polyubiquitin comprises multiple covalently linked ubiquitins and recognizes myriad targets. Free or bound to ligands, polyubiquitins are found in different arrangements of ubiquitin subunits. To understand the structural basis for polyubiquitin quaternary plasticity and to explore the target recognition mechanism, we characterize the conformational space(More)
PURPOSE Transforming growth factor (TGF) -β1 signaling is involved in cancer-cell metastasis. We investigated whether single nucleotide polymorphisms (SNPs) at TGFβ1 were associated with overall survival (OS) and distant metastasis-free survival (DMFS) in patients with non-small cell lung cancer (NSCLC) treated with definitive radiotherapy, with or without(More)
Vehicular Ad hoc Networks is a special kind of mobile ad hoc network to provide communication among nearby vehicles and between vehicles and nearby fixed equipments. VANETs are mainly used for improving efficiency and safety of (future) transportation. There are chances of a number of possible attacks in VANET due to open nature of wireless medium. In this(More)
BACKGROUND MUC5B is glycoprotein secreted by bronchial glands. A promoter variant in MUC5B, rs35705950, was previously found to be strongly associated with the incidence of idiopathic pulmonary fibrosis (IPF) and also the overall survival (OS) of such patients. Patients with IPF and patients with radiation pneumonitis (RP) have the similar pathologic(More)
BACKGROUND Fractures are a common morbidity that lead to worse outcomes in dialysis patients. Fetuin A inhibits vascular calcification (VC), potentially promotes bone mineralization and its level positively correlates with bone mineral density in the general population. On the other hand, the presence of VC is associated with low bone volume in dialysis(More)
Specific cell surface labeling is essential for visualizing the internalization processes of G-protein coupled receptors (GPCRs) and for gaining mechanistic insight of GPCR functions. Here we present a rapid, specific, and versatile labeling scheme for GPCRs at living-cell membrane with the use of a split green fluorescent protein (GFP). Demonstrated with(More)