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This paper presents an extension of the capacitated facility location problem (CFLP), in which the general setup cost functions and multiple facilities in one site are considered. The setup costs consist of a fixed term (site setup cost) plus a second term (facility setup costs). The facility setup cost functions are generally non-linear functions of the(More)
Ubiquitin-specific protease 22 (USP22), a novel deubiquitinating enzyme, has been associated with metastasis, therapy resistance, and cell cycle progression. The purpose of this study was to investigate the expression level of USP22 in papillary thyroid carcinoma (PTC) samples and to evaluate its clinical significance in PTC patients. USP22 expression was(More)