Ju. I. Shilov

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The intensity of lymphocyte proliferation in response to pokeweed mitogen depends on cortisol level in the peripheral blood in the early post-traumatic period of penetrating eye injury. Lymphocyte proliferation in 72- and 96-h cultures from patients with high levels of endo genous hormone was suppressed. In 120-h cultures, the intensity of proliferation(More)
Myelopid and MP-1 myelopeptide increase the count of antibody-producing cells, reduced under the effect of injury and standard therapy, and do not modify the suppression of delayed hypersensitivity. Injections of myelopid and MP-3 together with standard drugs optimized the traumatic inflammation processes.
Glucocorticoids and adrenaline, the major stress hormones, exert synergic effects on the immune system. In particular, they unidirectionally affect the production of interleukin-12, interferonγ , and some other cytokines [1, 2]. On the other hand, the interaction between the effects of these hormones may depend on glucocorticoid-induced changes in the(More)
304 Penetrating eye injury (PEI) is an example of spa tially limited injury entailing not only local responses, including impairment of immunosuppression mecha nisms in this immunologically privileged organ itself, but also systemic stress related changes in the immune system in response to the hazard of the loss of an organ important for receiving(More)
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