Learn More
Companies innovating in agriculture-related biotechnology currently confront a complicated and controversial policy environment. Using analytical frameworks of technological trajectories and paradigms this paper examines R&D strategy in large companies. A large research project found that R&D related decisions taken by managers reflect company(More)
B iofuels made from renewable biomass are promoted as offering greenhouse gas (GHG) emissions savings and as one of the few options to replace liquid fossil fuels for transport. Mandatory targets for introduction and blending of biofuels have been introduced. For example, renewable fuels must account for 10% of transport fuel by 2020 in the European Union(More)
The pharmaceutical and agro-biotechnology industries have been confronted by dwindling product pipelines and rapid developments in life sciences, thus demanding a strategic rethink of conventional research and development. Despite offering both industries a solution to the pipeline problem, the life sciences have also brought complex regulatory challenges(More)
OBJECTIVES To estimate the potential economic impact of pandemic influenza, associated behavioural responses, school closures, and vaccination on the United Kingdom. DESIGN A computable general equilibrium model of the UK economy was specified for various combinations of mortality and morbidity from pandemic influenza, vaccine efficacy, school closures,(More)
The creation of red blood cells for the blood transfusion markets represents a highly innovative application of regenerative medicine with a medium term (5-10 year) prospect for first clinical studies. This article describes a case study analysis of a project to derive red blood cells from human embryonic stem cells, including the systemic challenges(More)
Scientific advances in methods of producing genetically modified (GM) animals continue, yet few such animals have reached commercial production. Existing regulations designed for early techniques of genetic modification pose formidable barriers to commercial applications. Radically improved techniques for producing GM animals invite a re-examination of(More)
Food security has become an issue of serious concern because global food supplies are threatened by systemic collapse. increasing demand for food caused by global population growth, changing lifestyles in developing countries, climate change and competition with bio fuels are combining to create a ‘perfect storm’ (godfray et al, 2010). Moreover, short-term(More)
Regulatory decision-making over the use of products of new technology aims to be based on science-based risk assessment. In some jurisdictions, decision-making about the cultivation of genetically modified (GM) plants is blocked supposedly because of scientific uncertainty about risks to the environment. However, disagreement about the acceptability of(More)
Stratified medicine offers both opportunities and challenges to the conventional business models that drive pharmaceutical R&D. Given the increasingly unsustainable blockbuster model of drug development, due in part to maturing product pipelines, alongside increasing demands from regulators, healthcare providers and patients for higher standards of safety,(More)