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The pharmaceutical and agro-biotechnology industries have been confronted by dwindling product pipelines and rapid developments in life sciences, thus demanding a strategic rethink of conventional research and development. Despite offering both industries a solution to the pipeline problem, the life sciences have also brought complex regulatory challenges(More)
Stratified medicine offers both opportunities and challenges to the conventional business models that drive pharmaceutical R&D. Given the increasingly unsustainable blockbuster model of drug development, due in part to maturing product pipelines, alongside increasing demands from regulators, healthcare providers and patients for higher standards of safety,(More)
Multinational companies in the life science sector are heavily influenced by government policies and regulations and in turn attempt to influence these actors nationally and internationally. This paper focuses on recent and ongoing research, principally on the agro-biotechnology and, to a lesser extent, on the pharmaceutical industries, covering the(More)
outlook outlook F ood security has become an issue of serious concern because global food supplies are threatened by systemic collapse. increasing demand for food caused by global population growth, changing lifestyles in developing countries, climate change and competition with bio fuels are combining to create a 'perfect storm' (godfray et al, 2010).(More)
Regulatory decision-making over the use of products of new technology aims to be based on science-based risk assessment. In some jurisdictions, decision-making about the cultivation of genetically modified (GM) plants is blocked supposedly because of scientific uncertainty about risks to the environment. However, disagreement about the acceptability of(More)
OBJECTIVES To estimate the potential economic impact of pandemic influenza, associated behavioural responses, school closures, and vaccination on the United Kingdom. DESIGN A computable general equilibrium model of the UK economy was specified for various combinations of mortality and morbidity from pandemic influenza, vaccine efficacy, school closures,(More)
Companies innovating in agriculture-related biotechnology currently confront a complicated and controversial policy environment. Using analytical frameworks of technological trajectories and paradigms this paper examines R&D strategy in large companies. A large research project found that R&D related decisions taken by managers reflect company(More)
To the Editor: Experience has shown that early-stage choices made in setting up regulatory systems in the life sciences can, in unanticipated ways, determine the eventual scope for innovation and the delivery of public benefits from scientific discoveries1,2. An example is stem cell science and regenerative medicine therapies where, although the UK(More)