OBJECTIVES High-grade serous ovarian cancer (HGSOC) mostly presents at an advanced stage and has a low overall survival rate. However, a subgroup of patients are seemingly cured after standard initial therapy. We hypothesize that the molecular profiles of these patients vary from long-term survivors who recur. METHODS Patients with advanced HGSOC who… (More)
Fused positron emission tomography and computed tomography scan showed a hypermetabolic lesion in the sigmoid colon, with no evidence of metastatic disease elsewhere.
Although high-grade serous carcinoma involving the ovary historically was thought to originate from the ovarian surface epithelium, a growing body of literature suggests that a large proportion may arise from fallopian tube secretory epithelial cells (FTSECs) and be better termed high-grade pelvic serous carcinoma (HGPSC). The clinical ramifications of… (More)