Joyce N. Barlin

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OBJECTIVES High-grade serous ovarian cancer (HGSOC) mostly presents at an advanced stage and has a low overall survival rate. However, a subgroup of patients are seemingly cured after standard initial therapy. We hypothesize that the molecular profiles of these patients vary from long-term survivors who recur. METHODS Patients with advanced HGSOC who(More)
Although high-grade serous carcinoma involving the ovary historically was thought to originate from the ovarian surface epithelium, a growing body of literature suggests that a large proportion may arise from fallopian tube secretory epithelial cells (FTSECs) and be better termed high-grade pelvic serous carcinoma (HGPSC). The clinical ramifications of(More)
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