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BACKGROUND This study assesses the utility of a hybrid optical instrument for noninvasive transcranial monitoring in the neurointensive care unit. The instrument is based on diffuse correlation spectroscopy (DCS) for measurement of cerebral blood flow (CBF), and near-infrared spectroscopy (NIRS) for measurement of oxy- and deoxy-hemoglobin concentration.(More)
—Reliability, power consumption and timing performance are key considerations for the utilisation of field-programmable gate arrays. Online measurement techniques can determine the timing characteristics of an FPGA application while it is operating, and facilitate a range of benefits. Degradation can be monitored by tracking changes in timing performance,(More)
  • Robert Siman, Nicholas Giovannone, Nikhil Toraskar, Suzanne Frangos, Sherman C. Stein, Joshua M. Levine +1 other
  • 2011
Biomarkers for neurodegeneration could be early prognostic measures of brain damage and dysfunction in aneurysmal subarachnoid hemorrhage (aSAH) with clinical and medical applications. Recently, we developed a new panel of neurodegeneration biomarkers, and report here on their relationships with pathophysiological complications and outcomes following severe(More)
Shadow registers, driven by a variable-phase clock, can be used to extract useful timing information from a circuit during operation. This paper presents Slack Measurement Insertion (SMI), an automated tool flow for inserting shadow registers into an FPGA design to enable measurement of timing slack. The flow provides a parameterised level of circuit(More)
Timing margins in FPGAs are already significant and as process scaling continues they will have to grow to guarantee operation under increased variation. Margins enforce worst-case operation even in typical conditions and result in devices operating more slowly and consuming more energy than necessary. This paper presents a method of dynamic voltage and(More)
  • James S. McKinney, Steven R. Messé, Bryan A. Pukenas, Sudhakar R. Satti, John B. Weigele, Robert W. Hurst +3 others
  • 2010
Background. Cervicocephalic arterial dissection (CCAD) is rare in the postpartum period. To our knowledge this is the first reported case of postpartum angiopathy (PPA) presenting with ischemic stroke due to intracranial arterial dissection. Case. A 41-year-old woman presented with blurred vision, headache, and generalized seizures 5 days after delivering(More)
We propose the compile-time instrumentation of coexisting modules?IP blocks, accelerators, etc.?implemented in FPGAs. The efficient mapping of tasks to execution units can then be achieved, for power and/or timing performance, by tracking dynamic power consumption and/or timing slack online at module-level granularity. Our proposed instrumentation is(More)
The on-chip timing behaviour of synchronous circuits can be quantified at run-time by adding shadow registers, which allow designers to sample the most critical paths of a circuit at a different point in time than the user register would normally. In order to sample these paths precisely, the path skew between the user and the shadow register must be(More)