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A detailed analysis of mode-locking is presented in which the nonlinear mode-coupling behavior in a waveguide array, dual-core fiber, and/or fiber array is used to achieve stable and robust passive modelocking. By using the discrete, nearest-neighbor spatial coupling of these nonlinear mode-coupling devices, low-intensity light can be transferred to the(More)
To study the effects of malaria-control interventions on parasite population genomics, we examined a set of 1,007 samples of the malaria parasite Plasmodium falciparum collected in Thiès, Senegal between 2006 and 2013. The parasite samples were genotyped using a molecular barcode of 24 SNPs. About 35% of the samples grouped into subsets with identical(More)
Extracting governing equations from data is a central challenge in many diverse areas of science and engineering. Data are abundant whereas models often remain elusive, as in climate science, neuroscience, ecology, finance, and epidemiology, to name only a few examples. In this work, we combine sparsity-promoting techniques and machine learning with(More)
A novel mode-locking technique is presented in which the intensity-dependent spatial coupling dynamics of a waveguide array is used to achieve temporal mode-locking in a passive optical fiber laser. By use of the discrete, nearest-neighbor spatial coupling of the waveguide array, low-intensity light can be transferred to the neighboring waveguides and(More)
BACKGROUND The development and application of quantitative methods to understand disease dynamics and plan interventions is becoming increasingly important in the push toward eradication of human infectious diseases, exemplified by the ongoing effort to stop the spread of poliomyelitis. METHODS Dynamic mode decomposition (DMD) is a recently developed(More)
The haemozoin crystal continues to be investigated extensively for its potential as a biomarker for malaria diagnostics. In order for haemozoin to be a valuable biomarker, it must be present in detectable quantities in the peripheral blood and distinguishable from false positives. Here, dark-field microscopy coupled with sophisticated image processing(More)
Systems without Koopman-invariant subspaces that explicitly span the state For any system with multiple fixed points, periodic orbits, or atrracting/repelling structures, there is no finite-dimensional Koopman invariant subspace that explicitly includes the state. This follows from the fact that these systems cannot be topologically conjugate to a(More)