Jacqueline Canning Tilly3
Yuichi Niikura3
Malgorzata Skaznik-Wikiel3
3Jacqueline Canning Tilly
3Yuichi Niikura
3Malgorzata Skaznik-Wikiel
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It has been suggested that germline stem cells maintain oogenesis in postnatal mouse ovaries. Here we show that adult mouse ovaries rapidly generate hundreds of oocytes, despite a small premeiotic germ cell pool. In considering the possibility of an extragonadal source of germ cells, we show expression of germline markers in bone marrow (BM). Further, BM(More)
Of all the 'certainties' in mammalian female reproductive biology, the concept that a non-renewing oocyte reserve is set forth in the ovaries at birth may be the most longstanding and widely held. However, when data from our studies of oocyte apoptosis unintentionally began to contradict this theory in the latter part of 2002, we embarked on an(More)
A major challenge in developing vaccines for emerging pathogens is their continued evolution and ability to escape human immunity. Therefore, an important goal of vaccine research is to advance vaccine candidates with sufficient breadth to respond to new outbreaks of previously undetected viruses. Ebolavirus (EBOV) vaccines have demonstrated protection(More)
We have shown that inhibition of mTOR in granulosa cells and ovarian follicles results in compromised granulosa proliferation and reduced follicle growth. Further analysis here using spontaneously immortalized rat granulosa cells has revealed that mTOR pathway activity is enhanced during M-phase of the cell cycle. mTOR specific phosphorylation of p70S6(More)
A recent commentary in this journal by Byskov et al. (2005) claims that, despite published results from numerous independent lines of investigation from our laboratory and others, there does not "exist any evidence for neo-folliculogenesis in the adult mammalian ovary." While we agree with Byskov et al. that our work represents a radical departure from the(More)
An age-independent division of labor can develop in both the reproductive (queen) and non-reproductive (worker) castes of Pogonomyrmex californicus harvester ants, and individuals develop biases for in-nest activities or external foraging. Additionally, ant ovaries normally atrophy in foragers compared to nest-biased workers (nurses). However, it is not(More)
This study examined the extent to which patterns of mood and daily stress experienced by individuals with compulsive buying (CB) are associated with CB episodes by using Ecological Momentary Assessment. The comparison of mood and the impact of daily stress on days on which CB occurred to those days on which CB episodes did not occur did not reveal any(More)
The cardiac glycosides ouabain and digitoxin, established Na(+)/K(+) ATPase inhibitors, were found to inhibit MDA-MB-231 breast cancer cell migration through an unbiased chemical genetics screen for cell motility. The Na(+)/K(+) ATPase acts both as an ion-transporter and as a receptor for cardiac glycosides. To delineate which function is related to breast(More)
  • Md Abdullah Yousuf Al Harun, Joshua Johnson, Md Nazim Uddin, Randall W. Robinson, Sergio R. Roiloa
  • 2015
Chrysanthemoides monilifera subsp. monilifera (boneseed), a weed of national significance in Australia, threatens indigenous species and crop production through allelopathy. We aimed to identify phenolic compounds produced by boneseed and to assess their phytotoxicity on native species. Phenolic compounds in water and methanol extracts, and in decomposed(More)
Negative plant–plant interactions through the release of allelochemicals via leaching, decomposition of residues in soil, volatilization and exudation are well established. We aimed to characterise the allelopathic potential of Chrysanthemoides monilifera subsp. monilifera (boneseed) in terms of volatilization and exudation. A series of bioassays compared(More)