Joshua DiPaolo

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Imperatives cannot be true, but they can be obeyed or binding: ‘Surrender!’ is obeyed if you surrender and is binding if you have a reason to surrender. A pure declarative argumentwhose premisses and conclusion are declarativesis valid exactly if, necessarily, its conclusion is true if the conjunction of its premisses is true; similarly, I suggest, a pure(More)
This study delineates differences in biologic activity between human papillomavirus (HPV) types 16 and 18. Human cervical and foreskin epithelial cells were cultured and transfected with recombinant HPV-16 and -18 DNA, resulting in immortalized cell lines. Normal epithelial cells as well as HPV-16 and -18 immortalized cells of both early passages (less than(More)
Kadri Vihvelin, in “What time travelers cannot do” (1996), argued that “no time traveler can kill the baby who in fact is her younger self”, because (V1) “if someone would fail to do something, no matter how hard or how many times she tried, then she cannot do it”, and (V2) if a time traveler tried to kill her baby self, she would always fail. Theodore(More)
Polymorphism of the human papillomavirus type 16 (HPV-16) genome has been reported to occur within the noncoding regulatory long control region (LCR) and in the E7 and L1 genes. The current study focuses on the HPV-16 E6 oncogene which interacts with the antioncogenic regulator p53. Seventy-eight HPV-16-positive DNA samples derived from cervical carcinomas(More)
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