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A method for planning smooth robot paths is presented. The method relies on the use of Laplace's Equation to constrain the generation of a potential function over regions of the connguration space of an eeector. Once the function is computed, paths may be found very quickly. These functions do not exhibit the local minima which plague the potential eld(More)
This paper presents a new approach to the extraction of straight lines in intensity images. Pixels are grouped into line-support regions of similar gradient orientation, and then the structure of the associated intensity surface is used to determine the location and properties of the edge. The resulting regions and extracted edge parameters form a low-level(More)
Childhood onset motor neuron diseases or neuronopathies are a clinically heterogeneous group of disorders. A particularly severe subgroup first described in 1894, and subsequently called Brown-Vialetto-Van Laere syndrome, is characterized by progressive pontobulbar palsy, sensorineural hearing loss and respiratory insufficiency. There has been no treatment(More)
AIM Motor skill impairment and cognitive dysfunction are commonly reported features of neurofibromatosis type 1 (NF1). We characterized and determined the relationship between motor impairment, gait variables, and cognitive function in children and adolescents with NF1. METHOD Motor function, gait, and neurocognitive abilities were assessed in 46 children(More)
BACKGROUND Interactive Health Communication Applications (IHCAs) are computer-based, usually web-based, information packages for patients that combine health information with at least one of social support, decision support, or behaviour change support. These are innovations in health care and their effects on health are uncertain. OBJECTIVES To assess(More)
[Burgi94] P.-Y. Burgi and T. Pun, " Asynchronous image analysis: using the relationship luminance-to-latency to improve segmentation " , J. Promising directions in active vision " , Int. [Thorpe90] S.J. Thorpe, " Spike arrival times: A highly efficient coding scheme for neural networks " , In: R. 12 The final result of the dynamic indexing process is a(More)
Health-related, quality of life (HRQoL) is an important outcome in clinical trials of patients with Charcot-Marie-Tooth disease (CMT). In a cross-sectional survey of 295 Australian adults with CMT, HRQoL was measured using the Short Form-36 (SF-36) and predictors of reduced HRQoL were identified with a CMT-specific health status questionnaire. People with(More)
Immunization of experimental animals with myelin basic protein (MBP) or with specific MBP encephalitogenic determinants induces an autoimmune central nervous system (CNS) disease, experimental allergic encephalomyelitis, often studied as a model for human demyelinating disorders. This study examines the antigenic determinants of MBP recognized by human T(More)
Some bacteria that are common human pathogens produce protein toxins that are potent activators of human T lymphocytes expressing certain types of T-cell receptors. In this study we examined the ability of staphylococcal toxins to stimulate human T lymphocytes that also recognized the myelin autoantigens myelin basic protein and proteolipid protein. T-cell(More)