Joshimol Clement

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The forced pseudo-random noise oscillation technique is a method by which total respiratory resistance (Rrs) and reactance (Xrs) can be measured simultaneously at various frequencies by means of complex oscillations, superimposed at the mouth during spontaneous quiet breathing. Reference values were obtained in 255 healthy Caucasian children of Dutch(More)
Senile lungs are characterized by a homogeneous enlargement of the alveolar airspaces, without fibrosis or destruction of their walls. Study of the functional characteristics of excisea senile lungs showed an increase in minimal air and a shift to the left of the elastic recoil pressure-volume curves, less pronounced than in emphysematous lungs. Maximal(More)
The application of the forced oscillation technique to assess reversibility of airflow obstruction was compared with that of indices of forced expiration and plethysmographic airway resistance (Raw). In 125 patients with airflow obstruction, we measured total respiratory resistance (Rrs) and reactance (Xrs), Raw and specific airway conductance (sGaw),(More)
A comparison was made of total respiratory resistance (Rrs) and reactance (Xrs) determined between 6 and 26 Hz by means of a forced oscillation technique in 27 patients with asthma (group A), 28 patients with chronic bronchitis (group B), and 20 patients with emphysema (group E) to examine whether the method can provide data capable of distinguishing among(More)
In a prospective study of 2,406 members of the Belgian Air Force, followed for 3 to 15 yr, 325 demonstrated a yearly decline in FEV1 and/or in vital capacity (VC) that was significantly faster than that expected in healthy nonsmokers. Such rapid declines were met more frequently in heavy smokers and in subjects with a reduced FEV1 or VC. There was no(More)
In a study of two groups of healthy males matched for age, smoking habits, and duration of follow-up, but differing in the rapidity of decline of FEV1 and/or vital capacity (VC), we measured lung volumes before and after bronchodilator inhalation, forced expiratory flows, diffusion capacity for CO (DLCO), and total respiratory impedance. A discriminant(More)
The purpose of this study was to determine whether the forced oscillation technique is more sensitive than spirometry to detect lung function alterations in subjects with respiratory complaints. The input impedance of the respiratory system (between 2 and 24 Hz) and maximal expiratory flows and volumes were measured in 1,255 subjects referred for routine(More)
In 54 patients with interstitial lung diseases and no signs of airway obstruction we measured lung volumes, maximal expiratory flows, diffusing capacity (DLCO), total respiratory resistance (Rrs) and reactance (Xrs) between 4 and 26 Hz by means of the forced oscillation technique. In all patients DLCO was less than 75% of the expected value. Patients were(More)
A comparison was made of the frequency dependence of total respiratory resistance, (Rrs), and reactance (Xrs), determined by a forced oscillation technique in 442 healthy subjects and in 126 patients with respiratory complaints, with or without slight airways obstruction. The comparison was performed by means of a discriminant analysis. The latter(More)
As part of a study of the structural-functional correlations of excised human lungs obtained at autopsy, the parenchyma and peripheral airways were examined by means of morphometric techniques. Among the 30 lungs characterized by the absence of fibrosis, ten differed from the normal and emphysematous lungs by a homogeneous dilatation of the airspaces, in(More)