Josh Coe

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The authors have previously reported in vitro testing of various posterior and anterior constructs (sublaminar, Rogers', and Bohlman's triple-wire wiring; AO hook plate fixation; and Caspar anterior plate fixation) in a bovine model with multiaxial biomechanical testing. This study was undertaken to evaluate the above constructs and other constructs in(More)
The Saccharomyces cerevisiae SNF2/SWI2 protein is essential for the regulated expression of a variety of genes. A human SWI2/SNF2 homologue, hBrm, is a positive participant in glucocorticoid-receptor-mediated transcription, but its mechanism of action is not known. The retinoblastoma protein, RB, has also been shown to stimulate the transcription of several(More)
Posteriorly directed load to failure testing of four different types of spinal implants was performed in individual T5 to S1 vertebra harvested from seven fresh-frozen human cadaveric spines. The implants tested were: 1) Drummond spinous process wires, 2) Harrington laminar hooks, 3) Cotrel-Dubousset transpedicular screws, and 4) Steffee VSP transpedicular(More)
Cultural problems exist with current online systems for meeting new people, such as dating sites, which encourage unnatural meetings with strangers. An SMS-based murder mystery game was designed to facilitate the natural progression of growing one's personal network by meeting friends of friends. Considerations on how a location-based mobile system could(More)
OBJECTIVE The goal of this study was to use mice expressing human tissue factor pathway inhibitor (TFPI) on α-smooth muscle actin (α-SMA)(+) cells as recipients of allogeneic aortas to gain insights into the cellular mechanisms of intimal hyperplasia (IH). METHODS AND RESULTS BALB/c aortas (H-2(d)) transplanted into α-TFPI-transgenic (Tg) mice (H-2(b))(More)
Neurohistologic examination of the spinal cord and cauda equina were compared for 28 beagles undergoing anterior and posterior spinal destabilization procedures--Group I (n = 7), destabilized operative controls; Group II (n = 7), posterolateral bone grafting; Group III (n = 7), Harrington distraction instrumentation and posterolateral fusion; and Group IV(More)
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