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BACKGROUND Delayed presentation to hospital after an acute stroke is a major explanation given for low thrombolysis rates. This study aimed to investigate the factors associated with delays in presentation after an acute stroke and changes after a mass media campaign. METHODS AND RESULTS Data were from a population-based study involving 1392 patients with(More)
Background The transumbilical route began being clinically feasible with or without unique access devices. Setting The setting for this study was a private practice at Clínica Las Condes, Santiago, Chile. Objective The objective was to describe our experience performing a laparoscopic sleeve gastrectomy (LSG) via transumbilical route using a single-port(More)
A study was made of touch domes in the lumbar skin of rats of different ages. The mean density of the domes in 11- to 29-day-old rats ("pups") was 43.1 +/- 16.6/cm2 and was approximately four times higher than that in adult animals (11.6 +/- 2.8/cm2); no loss of domes appeared to have taken place in the oldest animals examined (21 months). By repeating(More)
BACKGROUND AND OBJECTIVE We present the case of a female patient 29 years of age with antecedents of laparoscopic laser ablation for endometriosis, laparoscopic appendectomy, and umbilical hernioplasty. METHODS The patient was admitted to the hospital's emergency room for abdominal pain in the epigastrium, transfixing, irradiating to both upper quadrants(More)
Given the high costs of conducting a drug-response trial, researchers are now aiming to use retrospective analyses to conduct genome-wide association studies (GWAS) to identify underlying genetic contributions to drug-response variation. To prevent confounding results from a GWAS to investigate drug response, it is necessary to account for concomitant(More)
The responses of touch domes in hairy skin of the rat to mechanical stimulation were examined after single doses of vincristine sulfate. Within 24 h of drug administration, the mean thresholds of domes to brief mechanical pulses had increased threefold, from 5.2 +/- 2.0 to 14.2 +/- 8.8 microns. This elevated threshold was maintained for 2 weeks but by the(More)
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