JosephW. Golden

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PURPOSE To determine the optimal dose and treatment outcome of patients treated with radiation for intracranial germinoma. METHODS AND MATERIALS Between 1975 and 1995, 40 patients with the diagnosis of intracranial germinoma were treated with radiation (RT) to the central nervous system. All patients received whole-brain (WB) RT (median dose: 32.4 Gy,(More)
Chronic subdural hematoma (CSDH) with membranes is a common problem in neurosurgery. Despite its frequency, the pathogenesis of this lesion is poorly understood. We conducted a systematic pathologic review, with clinical correlation, of all CSDH presenting to our institution over a two-year period which had undergone pathological examination. Surprisingly,(More)
The mechanisms governing growth of cavernous angiomas of the brain and their propensity to hemorrhage remain unknown. Repetitive hemorrhage with neovascularization during clot organization and maturation of new vessels into a larger cavernous angioma has been hypothesized as one mechanism. This hypothesis is largely based on the histopathological similarity(More)
Human pathogenic hantaviruses and arenaviruses are maintained in nature by persistent infection of rodent carrier populations. Several members of these virus groups can cause significant disease in humans that is generically termed viral hemorrhagic fever (HF) and is characterized as a febrile illness with an increased propensity to cause acute(More)
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