We have developed a methodology we call ROMA (representational oligonucleotide microarray analysis), for the detection of the genomic aberrations in cancer and normal humans. By arraying oligonucleotide probes designed from the human genome sequence, and hybridizing with "representations" from cancer and normal cells, we detect regions of the genome with… (More)
We describe a method to make physical maps of genomes using correlative hybridization patterns of probes to random pools of BACs. We derive thereby an estimated distance between probes, and then use this estimated distance to order probes. To test the method, we used BAC libraries from Schizzosaccharomyces pombe. We compared our data to the known sequence… (More)
The present study describes an Arabic cross-cultural validation of the Beck Depression Inventory. An Arab sample of 53 cases was subjected to the original validation procedures which involved a preliminary exercise and a translation from English to Arabic. Acceptable equivalent meanings of Beck's depth-of-depression criteria were established by the Arab… (More)
A disproportionate number of Euro-American inmates given either an amphetamine- or cocaine-abuse diagnosis upon admission to prison were given a diagnosis of amphetamine abuse. A disproportionate number of African-American inmates were given a cocaine-abuse diagnosis. Of the 800 consecutively admitted inmates who were given one diagnosis or the other, 68%… (More)
Of 206 convicted sex offenders in a men's prison a disproportionate number of child molesters were white and a disproportionate number of rapists were black. Of the 758 inmates in general, a disproportionate number of both child molesters and rapists were white (n = 171 vs 35 black men).
This study compares the responses to a self-report depression inventory administered to a sample of 243 Saudi and American expatriate psychiatric outpatients of a large Eastern Province medical centre in Saudi Arabia. The inventory was developed by Beck et al. (1961), and the Arabic language form was validated by West and Al-Kaisi (1982). A Kruskal-Wallis… (More)