Joseph Tjan

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PURPOSE To examine the efficacy of antagonism of rapacuronium-, mivacurium-, rocuronium- and cisatracurium-induced neuromuscular block at the laryngeal adductors (LA). METHODS One hundred four patients were randomly assigned to one of eight study groups. They either received rapacuronium 1.5 mg x kg(-1), mivacurium 0.25 mg x kg(-1), rocuronium 0.9 mg x(More)
Evidence has been presented that inhibition by diclofenac sodium of the production of leukotrienes by cells participating in the inflammatory process is due to a decreased availability of intracellular arachidonic acid which results from enhanced uptake of the substrate into triglyceride pools. The diminished leukotriene production does not result from(More)
BACKGROUND An ultrashort-acting nondepolarizing neuromuscular blocking agent that could be an alternative to succinylcholine has been the focus of a concerted effort in the field of muscle relaxants. GW280430A showed a promising pharmacodynamic profile in preclinical work and a wide margin of safety and so was selected for study in humans. METHODS(More)
Urea clearance was determined on 25 healthy male medical students at Surabaja, Indonesia. The age of the subjects varied from 20 to 25 years, the average being 23 years. The subjects reported to the laboratory at 8 a.m., when they voided urine and then rapidly drank 500 m!. of iced water. At 9 a.m. they passed urine which was collected and measured, and 5(More)
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