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  • James H. Tsai, John Tayu Lee, +35 authors Gideon Bollag
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2008 (First Publication: 26 February 2008)
  • BRAFV600E is the most frequent oncogenic protein kinase mutation known. Furthermore, inhibitors targeting “active” protein kinases have demonstrated significant utility in the therapeutic repertoireExpand