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Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae
Comprehensive identification of polymorphisms among individuals within a species is essential both for studying the genetic basis of phenotypic differences and for elucidating the evolutionaryExpand
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Genome evolution across 1,011 Saccharomyces cerevisiae isolates
Large-scale population genomic surveys are essential to explore the phenotypic diversity of natural populations. Here we report the whole-genome sequencing and phenotyping of 1,011 SaccharomycesExpand
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Genome-Wide Detection of Polymorphisms at Nucleotide Resolution with a Single DNA Microarray
A central challenge of genomics is to detect, simply and inexpensively, all differences in sequence among the genomes of individual members of a species. We devised a system to detect allExpand
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Genome-Wide Analysis of Nucleotide-Level Variation in Commonly Used Saccharomyces cerevisiae Strains
Ten years have passed since the genome of Saccharomyces cerevisiae–more precisely, the S288c strain–was completely sequenced. However, experimental work in yeast is commonly performed using strainsExpand
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Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus.
Reconstructing genome history is complex but necessary to reveal quantitative principles governing genome evolution. Such reconstruction requires recapitulating into a single evolutionary frameworkExpand
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de novo assembly and population genomic survey of natural yeast isolates with the Oxford Nanopore MinION sequencer
Abstract Background: Oxford Nanopore Technologies Ltd (Oxford, UK) have recently commercialized MinION, a small single-molecule nanopore sequencer, that offers the possibility of sequencing long DNAExpand
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The complete genome of Blastobotrys (Arxula) adeninivorans LS3 - a yeast of biotechnological interest
BackgroundThe industrially important yeast Blastobotrys (Arxula) adeninivorans is an asexual hemiascomycete phylogenetically very distant from Saccharomyces cerevisiae. Its unusual metabolicExpand
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Mitochondrial Genome Evolution in a Single Protoploid Yeast Species
Mitochondria are organelles, which play a key role in some essential functions, including respiration, metabolite biosynthesis, ion homeostasis, and apoptosis. The vast numbers of mitochondrial DNAExpand
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Population Genomic Analysis Reveals Highly Conserved Mitochondrial Genomes in the Yeast Species Lachancea thermotolerans
The increasing availability of mitochondrial (mt) sequence data from various yeasts provides a tool to study genomic evolution within and between different species. While the genomes from a range ofExpand
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Single-cell phenomics reveals intra-species variation of phenotypic noise in yeast
We describe the phenotypic diversity of S. cerevisiae morphology at single-cell resolution. Expand
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