Joseph Pointner

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BACKGROUND Two new prostate cancer markers, free-prostate specific antigen (f-PSA) and prostate specific membrane antigen (PSMA) were recently introduced. This report summarizes a prospective two-year multicenter test of their diagnostic or prognostic capabilities. Total PSA was also measured. METHODS There were four clinical groups studied: (1) 226(More)
Approximately 20% of prostate cancers originate in the transition zone (TZ). Although transrectal ultrasound (TRUS) and systematic biopsies have improved peripheral zone (PZ) cancer diagnosis, additional biopsies directed into the TZ may further improve cancer detection. To evaluate the frequency and clinical significance of TZ cancers, we added two TZ(More)
OBJECTIVES To compare bipolar and monopolar transurethral resection of the prostate (TURP) in a comparative prospective study at two urology centers. METHODS Of 212 patients with symptomatic benign prostatic hyperplasia entered prospectively into the study, 111 underwent bipolar and 101 monopolar TURP. Patients were treated in two consecutive series with(More)
OBJECTIVES This study was designed to compare the usefulness of the normal prostate-specific antigen (PSA) level and the age-referenced PSA level in a large screening study for early detection of prostate cancer. METHODS A total of 21,078 subjects (aged 45 to 75 years) were participants in a 1-year prostate cancer screening project with PSA as the initial(More)
OBJECTIVES To describe current results with Western blot assay for prostate specific membrane antigen (PSMA) using 7E11.C5 antibody and the development of an additional antibody measurement for PSMA by a new sandwich immunoassay. METHODS A population of patients from a screening group, from a difficult diagnostic group, from a pre- and postoperative(More)
OBJECTIVES Two different studies were performed. The aim of the first study was to define whether the measurement of the ratio between free and total prostate-specific antigen (f/t PSA) in serum may enhance the ability of PSA-based screening for early detection of prostate cancer in men with elevated serum PSA levels. A second study was undertaken to(More)
BACKGROUND The measurement of prostate specific antigen (PSA) is widely used in screening programs for early detection of prostate cancer. However the specificity for cancer detection is limited because serum PSA is also elevated in patients with benign prostatic-hyperplasia (BPH) and/or prostatitis. It has been shown recently, that the ratio of free/total(More)
A method of exciting the clitoris is described. After such a massage or stimulation of the clitoris, the cervix lumen enlarges and allows an easier passage. Thus one can assume that a reflex arc exists. Directions on how to arouse the "clitoris-cervix-reflex" can be requested by sending an international self addressed stamped envelope to the author.
BACKGROUND The efficacy and success of a screening program for prostate cancer in young and healthy asymptomatic volunteers are described. METHODS In the present study, prostate specific antigen (PSA) samples obtained from 2,272 males (aged 40-65 years) who donated blood at the local Red Cross Blood Bank were evaluated. Two groups of donors were(More)
Between December 1991 and November 1995 a total of 231 patients underwent laparoscopic varix ligation in our department. The laparoscopic varicocelectomy offers a lower rate of morbidity, allows for microscopic dissection with preservation of the spermatic artery and is amenable to bilateral ligation without a second incision. The spermatic arteries were(More)