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  • E Silverman, Sarah Eimerl, Joseph Orly
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 1999 (First Publication: 18 June 1999)
  • Steroidogenic acute regulatory protein (StAR) is a vital accessory protein required for biosynthesis of steroid hormones from cholesterol. The present study shows that in primary granulosa cells fromExpand
  • Noa Sher, Natalie Yivgi-Ohana, Joseph Orly
  • Biology, Medicine
  • Molecular endocrinology
  • 2007 (First Publication: 1 April 2007)
  • The first and key enzyme controlling the synthesis of steroid hormones is cholesterol side chain cleavage cytochrome P450 (P450scc, CYP11A1). This study sought to elucidate overlooked modes ofExpand
  • Yigal Farkash, Rina Timberg, Joseph Orly
  • Biology, Medicine
  • Endocrinology
  • 1986 (First Publication: 1 April 1986)
  • Rabbit antiserum to rat cytochrome P-450 cholesterol side chain cleavage (P-450scc) was produced without a previous biochemical purification of the enzyme. Instead, for immunization we used a singleExpand
  • Noa Goldring, J M Durica, +5 authors Joanne S. Richards
  • Biology, Medicine
  • Endocrinology
  • 1987 (First Publication: 1 May 1987)
  • Using an affinity-purified antibody against cholesterol side-chain cleavage P450 (P450scc) and a human P450scc cDNA probe, 11 rat P450scc cDNA clones were identified and isolated from our ratExpand