MicroRNAs (miRNAs) are small ( approximately 22 nucleotides) non-coding RNA strands that base pair with mRNA to degrade it or inhibit its translation. Because sleep and sleep loss induce changes in many mRNA species, we hypothesized that sleep loss would also affect miRNA levels in the brain. Rats were sleep-deprived for 8h then decapitated; hippocampus,… (More)
DESCRIPTION A 46-year-old woman presents for excision of a lesion over her left cheek that has been increasing in size over the past year.
To date, cognitive behavioral therapy has been designated the most efficient evidence-based psychotherapeutic approach for OCD management. This is mainly due to its ability to effectively address the constitutional and developmentally acquired emotional and cognitive deficiencies of OCD, which express themselves through behavioral compulsions and intrusive… (More)
The prospect of utilizing memory plasticity (the constructive and transitory nature of memory) for therapeutic purposes has not been widely recognized. However, a number of theoretical and clinical venues throughout the last century have shown its potential application. Intensive research conducted during these last decades, pointed out the possibility of… (More)
Psychological dissociation is commonly perceived by mental health professionals as the pathological splitting of consciences or as an impairment in adaptive integration. In hypnotherapy dissociation is considered one of the most significant features of hypnosis, constituting a major therapeutic resource. In the present article, we use hypnotically induced… (More)
An out-of-body experience (OBE) is a unique dissociative event in which the person feels separated from his/her body. Studies and anecdotal reports have observed that this experience tends to appear spontaneously in stressful and hypnogogic situations. It often contributes to the person's later having a new perspective of himself and his conception of the… (More)