Joseph Klancnik

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AIM To investigate the use of intravitreal triamcinolone acetonide (IVTA) for the treatment of diabetic macular oedema (DMO) unresponsive to previous laser photocoagulation. METHOD A retrospective, interventional, non-comparative case series. There were 30 eyes of 22 consecutive patients with refractory DMO. An intravitreal injection of triamcinolone(More)
This study investigated the effects of the serotonin (5-HT)precursor 5-hydroxytryptophan (5-HTP) and the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on population responses in the dentate gyrus evoked by perforant path stimulation. Intraperitoneal injections of either compound into urethane anesthetized rats produced a(More)
The effects of serotonin (5-HT), the 5-HT1A receptor subtype agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and the 5-HT2 receptor subtype agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on electrophysiological responses in the dentate gyrus and area CA1 were examined in the in vitro hippocampal slice preparation. Superfusion of(More)
The effects of median raphe nucleus (MRN) stimulation on the induction of long-term potentiation (LTP) was investigated in the dentate gyrus (DG) of urethane-anaesthetized rats. LTP of both DG population spike amplitude and population EPSP slope was induced when tetanic electrical stimulation (100 Hz, 1 s) of the perforant path (PP), at an intensity which(More)
In our clinical practice, we have also observed that some persons with DD at times experience a “dramatic and longlasting response to low-dose atypical neuroleptics” but that “this population, however, seems particularly sensitive to neuroleptic-induced movement disorders (NIMDs), hence caution and close monitoring are required” (1). What we feel deserves(More)
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