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In order to enhance the yield and productivity of metabolite production, researchers have focused almost exclusively on enzyme amplification or other modifications of the product pathway. However, overproduction of many metabolites requires significant redirection of flux distributions in the primary metabolism, which may not readily occur following product(More)
Oceanic dissolved organic carbon (DOC) constitutes one of the largest pools of reduced carbon in the biosphere. Estimated DOC export from the surface ocean represents 20% of total organic carbon flux to the deep ocean, which constitutes a primary control on atmospheric carbon dioxide levels. DOC is the carbon component of dissolved organic matter (DOM) and(More)
BACKGROUND The increasing availability of time series microbial community data from metagenomics and other molecular biological studies has enabled the analysis of large-scale microbial co-occurrence and association networks. Among the many analytical techniques available, the Local Similarity Analysis (LSA) method is unique in that it captures local and(More)
Biogeochemistry is the study of how living systems in combination with abiotic reactions process and cycle mass and energy on local, regional, and global scales (Schlesinger, 1997). Understanding how these biogeochemical cycles function and respond to perturbations has become increasingly important, as anthropogenic impacts have significantly altered many(More)
''Ecosystem'' turned eighty this July. When Tansley (1935) coined the term, he did so largely as a rejection of the concept of emergence as espoused by Phillips (1935). The Phillips paper actually came out a month after Tansley's, but Tansley was editor for the Journal of Ecology at the time and he published Phillip's paper with a footnote on the first page(More)
Introduction Conclusions References Tables Figures Back Close Full Screen / Esc This discussion paper is/has been under review for the journal Earth System Dynamics (ESD). Please refer to the corresponding final paper in ESD if available. Abstract Introduction Conclusions References Tables Figures Back Close Full Screen / Esc Abstract In this manuscript we(More)
Although microbial systems are well suited for studying concepts in ecological theory, little is known about how microbial communities respond to long-term periodic perturbations beyond diel oscillations. Taking advantage of an ongoing microcosm experiment, we studied how methanotrophic microbial communities adapted to disturbances in energy input over a(More)
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