Joseph Ippolito

Learn More
1 Background Heart disease is the leading cause of death in the developed world. Despite major strides made in the past decade regarding the treatment and prevention of heart disease, cardiac injury due to acute myocardial infarct (MI) remains a difficult and complicated problem to solve. When enough tissue damage occurs in the myocardium, the ability of(More)
Intermittent vagal nerve stimulation (VNS) has emerged as a potential therapy to treat cardiovascular diseases by delivering electrical stimulation to the vagus nerves. The purpose of this study was to investigate the electrophysiological changes in the atrium resulting from long-term intermittent VNS therapy in the chronic myocardial infarction (MI) rat(More)
Muscle growth and repair is accomplished by the satellite cell pool, a self-renewing population of myogenic progenitors. Functional heterogeneity within the satellite cell compartment and changes in potential with experimental intervention can be revealed by in vitro colony-forming cell (CFC) assays, however large numbers of colonies need to be assayed to(More)
  • 1