Joseph Erlanger

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The conducted action potential of mixed somatic nerve when recorded, after amplification, by the cathode ray oscillograph exhibits waves, the more constant and prominent of which, for the sake of convenience, have been designated alpha, beta, gamma and delta’ in the order of their n signated appearance (Erlanger, Gasser and Bishop, 1924). These waves have l(More)
Numerous experiments, performed in this laboratory during the last few years, upon the form of the action potential wave of nerve, have established the fact that the wave is built up of units, which we have designated as axon potential waves. The form of the potential-time curve, as led off from a point on the nerve, depends in part upon the distance of(More)
A review of the literature on depression of conduction in a nerve trunk reveals the fact that there is a more or less definite order in the susceptibilities of the various fibers. In a cocainized nerve, sensory fibers are described as being more easily depressed than motor fibers, and as having different thresholds among themselves, so that the time of(More)
Furthermore, it has ently homogeneous, been demonstrated that strips of heart muscle, apparcan be made to exhibit not only differences in conductivity depending upon the direction of the beat, but even unidirectional conductivity (Erlanger, 1906). The present experiments were carried out primarily in the hope of shedding some light on the conditions(More)
While experimenting with spinal root preparations of the bullfrog it was found that during the passage of a constant current a repetitive response was obtained more commonly from the sensory than from the motor fibers. The present paper presents evidence indicating that this difference is characteristic, and also experiments having as their end attempts to(More)
THE FACTS COLLECTED IN THE THIRD PART OF THIS PAPER JUSTIFY THE FOLLOWING CONCLUSIONS: (1) All of the cardinal symptoms of Stokes-Adams disease may be duplicated by heart-block resulting from a lesion in or near the auriculo-ventricular bundle of His, and by this alone. (2) No typical case of Stokes-Adams disease has been described in which heart-block(More)
Lewis/ in I9O8 , called attention " to the widespread misunderstanding of the relations which exist between respiration and blood pressure." He states that in books on the subject one finds usually only the results obtained by Einbrodt in the dog, and by Klemensiewicz in man. Essentially these consist of a rise of pressure during inspiration and a fall(More)
Studies with the cathode ra.y oscillograph have shown that the fibers composing a peripheral nerve range widely in their reactivities. For instance, a large nerve, such as the sciatic, contains fibers conducting at rates varying as widely as 50 to 1 with an even wider irritability range as determined by induction shocks. But neither in this nor in other(More)