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To develop and validate a vasopressin (AVP) receptor knockdown strategy, we infused an antisense oligodeoxynucleotide to the V1 subtype mRNA into the septum of male rats with osmotic minipumps and(More)
P-domain peptides, a new family of secretory polypeptides, have been identified mainly in the gastroenteropancreatic tract of humans, rodents, and amphibians as well as in amphibian skin. In the(More)
Antisense DNA has been successfully used in vivo to selectively inhibit expression of proteins in the brain. However, stressful side effects after oligodeoxynucleotide (ODN) application have been(More)