Isolated skeletal muscle ryanodine receptors (RyRs) complexed with the modulatory ligands, calmodulin (CaM) or 12-kDa FK506-binding protein (FKBP12), have been characterized by electron… (More)
A 12-kDa immunophilin (FKBP12) is an integral component of the skeletal muscle ryanodine receptor (RyR). The RyR is a hetero-oligomeric complex with structural formula (FKBP)4(Ryr1)4, where Ryr1 is… (More)
The transient species CH,S and HCS were studied by photoionization mass spectrometry. They were prepared in situ from CH$H by sequential hydrogen abstraction with fluorine atoms. CHzS was also… (More)
Calmodulin (CaM) is a regulator of the calcium release channel (ryanodine receptor) of the sarcoplasmic reticulum of skeletal and cardiac muscle. The locations where CaM binds on the surface of the… (More)
CF3OH, an important and controversial by-product of atmospheric decomposition of CF 3CFH2 ~HFC-134a! and other hydrofluorocarbons, has been examined by photoionization mass spectrometry. The… (More)
Counseling of laryngectomy patients was studied by a questionnaire survey among 294 fellows of the American Society for Head and Neck Surgery and otolaryngology house officers (77% attendings and 23%… (More)
The dihydrolipoyl transacetylase (E2p) component of the pyruvate dehydrogenase complex (PDC) of Escherichia coli is a multidomain polypeptide comprising a catalytic domain, a domain that binds… (More)
The threshold photoelectron spectrum (TPES) of HOBr has been obtained in the wavelength regions corresponding to the first and second ionization bands. The adiabatic ionization potential (IP) is… (More)
The vacuum ultraviolet photoionization mass spectrum of As, is presented, from the ionization threshold to 600 A. The apparent adiabatic ionization potential is ~8.49 eV, but the true value may be… (More)
A wide variety of imaging techniques is available to assess the presence or extent of disease in the geriatric patient. Modalities range from the simple radiograph to more invasive techniques that… (More)