Joseph B. Miller

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First described in 1881, Wernicke's encephalopathy continues to be an unrecognized and often misunderstood disease. The cause of Wernicke's encephalopathy is thiamine deficiency as a result of any nutritionally deficient state, though many physicians erroneously consider this disease to be confined only to alcoholics. Unfortunately, the syndrome is most(More)
INTRODUCTION Early, effective lactate clearance has been shown to be associated with improved mortality in patients with trauma, burns, and sepsis. We investigated whether early, high lactate clearance was associated with reduced mortality in post-cardiac arrest patients. METHODS We performed a retrospective analysis of post-cardiac arrest patients in an(More)
BACKGROUND Cannabinoid use is prevalent in the United States, with recent reports of increased usage among younger Americans. Traditionally, cannabinoids have been used recreationally or as antiemetics; however, recent reports suggest that chronic abuse can result in the paradoxical effect of a cyclic vomiting syndrome, termed cannabinoid hyperemesis. (More)
OBJECTIVE Investigators in France have developed a risk score to predict death or poor neurologic outcome after out-of-hospital cardiac arrest. The aim of this study is to externally validate this score in an independent patient population in the United States. DESIGN Retrospective, observational, cohort study. PATIENTS Patients being admitted to the(More)
The photoluminescence (PL) of size-purified silicon nanocrystals is measured as a function of temperature and nanoparticle size for pure nanocrystal films and polydimethylsiloxane (PDMS) nanocomposites. The temperature dependence of the bandgap is the same for both sample types, being measurably different from that of bulk silicon because of quantum(More)
OPINION STATEMENT Acute ischemic stroke is the most common cause of adult disability in the world and the third most common cause of death. Early restoration of perfusion to ischemic brain has been a highly successful strategy to decrease the disability associated with acute ischemic stroke. For acute stroke, intravenous (IV) tissue plasminogen activator(More)
STUDY OBJECTIVE The objective of this study was to determine factors that impact emergency department (ED) utilization among the most frequent ED users. METHODS This prospective observational study consisting of questionnaires was conducted in an urban ED with an annual census of 95000 patients. A convenience sample of the top 1% of adult frequent users(More)
Wernicke's encephalopathy may result in severe morbidity and possible mortality when unrecognized. We report a distinctive acid-base pattern that has not been associated with this syndrome. This is a case series of patients with Wernicke's encephalopathy who had an arterial blood gas measurement performed on initial presentation. Exclusion criteria were(More)
Parastomal hernias can occur in up to 31% of patients following an enterostomy (Cheung in Aust N Z J Surg 65:808–811, 1995). This type of hernia develops through an intentional fascial defect. Commonly, most parastomal hernias involve a reducible segment of omentum, small bowel, or colon. Typically, these hernias are asymptomatic and associated rarely with(More)
We report on the quantum yield, photoluminescence (PL) lifetime, and ensemble photoluminescent stability of highly monodisperse plasma-synthesized silicon nanocrystals (SiNCs) prepared though density-gradient ultracentrifugation in mixed organic solvents. Improved size uniformity leads to a reduction in PL line width and the emergence of entropic order in(More)