Josep Daunis-i-Estadella

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BACKGROUND AND PURPOSE Early prediction of motor outcome is of interest in stroke management. We aimed to determine whether lesion location at DTT is predictive of motor outcome after acute stroke and whether this information improves the predictive accuracy of the clinical scores. MATERIALS AND METHODS We evaluated 60 consecutive patients within 12 hours(More)
BACKGROUND AND PURPOSE Little is known about the factors that determine recanalization after intravenous thrombolysis. We assessed the value of thrombus Hounsfield unit quantification as a predictive marker of stroke subtype and MCA recanalization after intravenous rtPA treatment. MATERIALS AND METHODS NCCT scans and CTA were performed on patients with(More)
Data fusion concerns the problem of merging information coming from independent sources. Also known as statistical matching, file grafting or microdata merging, it is a challenging problem for statisticians. The increasing growth of collected data makes combining different sources of information an attractive alternative to single source data. The interest(More)
BACKGROUND AND PURPOSE The quantification and clinical significance of WD in CSTs following supratentorial stroke are not well understood. We evaluated the anisotropy by using DTI and signal-intensity changes on conventional MR imaging in the CST to determine whether these findings are correlated with limb motor deficit in patients with MCA ischemic stroke.(More)
BACKGROUND AND PURPOSE Nearly 50% of patients have residual motor deficits after stroke, and long-term motor outcome is difficult to predict. We assessed the predictive value of axonal damage to the corticospinal tract indexed by diffusion tensor imaging fractional anisotropy for long-term motor outcome. METHODS Consecutive patients with middle cerebral(More)
BACKGROUND AND PURPOSE Infarct volume is used as a surrogate outcome measure in clinical trials of therapies for acute ischemic stroke. ABC/2 is a fast volumetric method, but its accuracy remains to be determined. We aimed to study the accuracy and reproducibility of ABC/2 in determining acute infarct volume with diffusion-weighted imaging. METHODS We(More)
Regression models with compositional response have been studied from the beginning of the log-ratio approach for analysing compositional data. These early approaches suggested the statistical hypothesis of logistic-normality of the compositional residuals to test the model and its coefficients. Also, the Dirichlet distribution has been proposed as an(More)
OBJECTIVE Rodent models have found that osteocalcin crosses the blood-brain barrier and regulates behaviour. No data are available on osteocalcin's effects on brain microstructure and cognitive performance in humans. We evaluated the association between serum osteocalcin concentrations and (i) brain microstructural changes on magnetic resonance imaging(More)
We qualitatively and quantitatively compared MRI enhancement obtained with gadofosveset, an albumin-binding blood-pool contrast agent, and with gadobutrol, an extracellular contrast agent, in patients with glioblastoma. Thirty-five patients (25 men; 64 ± 14 years) with histologically proven glioblastoma underwent MRI including pre- and post-contrast(More)
CONTEXT Growing evidence implicates hypothalamic inflammation in the pathogenesis of diet-induced obesity and cognitive dysfunction in rodent models. Few studies have addressed the association between obesity and hypothalamic damage in humans and its relevance. OBJECTIVE This study aimed to determine markers of obesity-associated hypothalamic damage on(More)