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BACKGROUND The reason behind a sudden death of a young individual remains unknown in up to 50% of postmortem cases. Pathogenic mutations in genes encoding heart proteins are known to cause sudden cardiac death. OBJECTIVE The aim of our study was to ascertain whether genetic alterations could provide an explanation for sudden cardiac death in a juvenile… (More)
The aim of our study consists of contributing information on the relationship between the personality variables derived from Gray's model and the conduct that accompanies the infringement of the road traffic rules. Seven hundred and ninety-two adults of both sexes took part in the study (389 men and 403 women), all of whom had driving licences and drove… (More)
Cardiovascular diseases are one of the main causes of death among middle-aged adults. In many cases, out-of-hospital sudden death is the first manifestation of the disease. The epidemiological characteristics of out-of-hospital sudden cardiovascular death are poorly defined. 1 The objective of the present study was to determine the incidence and causes of… (More)
[This corrects the article DOI: 10.1371/journal.pone.0167358.].
BACKGROUND Sudden unexplained death may be the first manifestation of an unknown inherited cardiac disease. Current genetic technologies may enable the unraveling of an etiology and the identification of relatives at risk. The aim of our study was to define the etiology of natural deaths, younger than 50 years of age, and to investigate whether genetic… (More)