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We determined the effects of dietary vitamin C supplementation on erythrocyte antioxidant enzymes and on plasma antioxidants during athletic competition and short-term recovery. Blood samples were taken from 16 volunteer endurance athletes, participating in a duathlon competition, under basal conditions and both immediately and 1 h after the competition.(More)
The aim of this work was to demonstrate the occurrence of oxidative stress during exhaustive exercise and to determine the antioxidant response. Eight voluntary male subjects participated in this study. The exercise was a cycling mountain stage (171 km) and the cyclists took a mean+/-S.E.M. time of 270+/-12 min to complete it. Blood samples were taken(More)
PURPOSE Supplementation with inorganic nitrate has been suggested to be an ergogenic aid for athletes as nitric oxide donor. The purpose of this study was to determine whether ingestion of inorganic sodium nitrate benefits well-trained athletes performing a 40-min exercise test in laboratory conditions. In addition, we investigated the effect of this(More)
Hydrogen peroxide (H2O2) could induce oxidative damage at long distance from its generation site and it is also an important signalling molecule that induces some genes related to oxidative stress. Our objective was to study the plasma and blood cells capability to detoxify H2O2 after intense exercise and its correlation with oxidative damage. Blood samples(More)
Cohort Profile: Design and methods of the PREDIMED study Miguel Ángel Martı́nez-González,1*y Dolores Corella, Jordi Salas-Salvadó, Emilio Ros, Marı́a Isabel Covas, Miquel Fiol, Julia Wärnberg, Fernando Arós, Valentina Ruı́z-Gutiérrez, Rosa Marı́a Lamuela-Raventós, Jose Lapetra, Miguel Ángel Muñoz, José Alfredo Martı́nez, Guillermo Sáez, Lluis Serra-Majem,(More)
BACKGROUND Exhaustive exercise induces oxidative stress. The cellular antioxidant defence systems have demonstrated great adaptation to chronic exercise. AIM To establish the influence of the antioxidant diet supplementation on the erythrocyte and lymphocyte antioxidant enzyme activities in athletes at basal and post-exercise levels. METHODS Fifteen(More)
OBJECTIVE The aim of this work was to check the effects of antioxidant supplementation (vitamins E and C, and beta-carotene) on the basal iron status of athletes prior to and following their training and competition season (3 months). DESIGN Eighteen amateur trained male athletes were randomly distributed in 2 groups: placebo (lactose) and antioxidant(More)
Nitric oxide (NO) has led a revolution in physiology and pharmacology research during the last two decades. This labile molecule plays an important role in many functions in the body regulating vasodilatation, blood flow, mitochondrial respiration and platelet function. Currently, it is known that NO synthesis occurs via at least two physiological pathways:(More)
Exercise induces changes in circulating pro- and anti-inflammatory cytokines. The aim was to investigate the effect of docosahexaenoic acid (DHA) diet supplementation on the plasma cytokine levels and on the peripheral mononuclear (PBMCs) cells cytokine production after a training season or an acute bout of exercise. Fifteen male soccer players were(More)
OBJECTIVE To assess prevailing food patterns among Balearic Islands' adolescents, and socio-economic and lifestyle determinants. DESIGN Cross-sectional nutritional survey carried out (2007-2008) in the Balearic Islands, a Mediterranean region. Dietary assessment was based on a 145-item semi-quantitative FFQ and two non-consecutive 24 h recalls.(More)