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INTRODUCTION Poor glycemic control and the resulting development of complications of type 2 diabetes (DM2T) increase treatment costs. If adequate glycemic control cannot be achieved by lifestyle modifications and oral antidiabetic (OAD) therapy, initiation of insulin therapy is recommended. Cost effectiveness of basal insulins of the type NPH or glargine in… (More)
Many patients with diabetes mellitus are treated by various medicinal products, which can in some cases lead to drug interaction. In this paper drug interactions of antidiabetics are summarised and most important drug interactions of other drugs frequently prescribed to diabetics are mentioned: drugs acting on the renin-angiotensin system and statins.
The growing consumption of drugs and other numerous factors relates to the increasing incidence of polypharmacy. The proportion of patients currently treated with 5 or more medicines at the elderly population in particular is 30-60% of patients. Repeatedly has been proven the dependence between the number of concomitant drugs and occurrence of adverse… (More)
AIM The main objective was to identify the occurrence of adverse events associated with amisulpride when combined with antidepressants (ADs). METHODS A non-interventional questionnaire-based study focussed on identification of occurrence and tolerance of combinations of amisulpride with ADs under common clinical practice conditions. RESULTS Combinations… (More)