Josef H. Hendriks

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BACKGROUND Although breast cancer screening is recommended to start at a younger age for women with a hereditary risk of breast cancer, the sensitivity of mammography for these women is reduced. We compared magnetic resonance imaging (MRI) with mammography to determine which is more sensitive and whether MRI could play a role in the early detection of(More)
Since January 1975 a population-based screening programme for the early detection of breast cancer has been carried out in the city of Nijmegen. During five interscreening periods of 2 years each a total of 158 so-called interval cancers were diagnosed. Careful revision of all screening and diagnostic mammograms was executed. Of all interval cancers 26%(More)
In some studies rationality, anti-emotionality and the control of (negative) emotions were found to be psychological risk factors for cancer. In the present study instruments were developed in order to cross-validate the role of the 'rationality/anti-emotionality (RAE)'-concept and the 'emotional expression and control (EEC)'-concept. The psychometric(More)
The use of mammography in recent years has resulted in an increase in the detection of small breast cancers. The beneficial effects of early detection on breast cancer mortality seem to differ with age. To obtain more insight into this matter we studied the long-term prognosis of patients with early invasive breast cancers (T1) in three age groups: 144(More)
The aim of this study was to investigate the extent to which the diagnosis of breast cancer influences the self-assessment of personality traits by patients. In 1989 and 1990, all female inhabitants of Nijmegen aged 43 years and over were invited to participate in a population screening for breast cancer and were asked to complete a personality(More)
After 10 years of screening for breast cancer by mammography in Nijmegen, the predictive value of positive screening results (PV+) was evaluated. The percentage of women with breast cancer in the group of referred women (PV+) for women under age 50 was 16-26%, regardless of the number of screening examinations they had. The percentage of women with breast(More)
show a considerable reduction of breast cancer mortality. But even though it is no longer disputed that early detection and early treatment lower the mortality of breast cancer, some problems remain to be solved. One of the problems inherent to screening is that a number of women who have been identified by mammo-graphy as suspect for having malignant(More)
We studied outcomes of mammographic screening in women older than 65 years. In 1975, breast cancer screening was started in Nijmegen, The Netherlands, for women aged 35-65 years. Since 1977, approximately 7700 older women have also been invited for biennial one-view mammography. This report is based on ten screening rounds from 1975 to 1994. The results of(More)
Current proposals for a monitoring and evaluation system in breast cancer screening programmes focus on mortality reduction. Here emphasis is laid on the prevention of too high a number of false-positive screening results, i.e. no subsequent demonstration of malignancy. By comparing the specificity of the screening test, the positive predictive value and(More)
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