Josef Eckmayr

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1 Medizinische Universität Innsbruck, Klinische Abteilung für Allgemeine Innere Medizin, Schwerpunkt Onkologie, Innsbruck, Österreich 2 KH der Elisabethinen Linz, Abteilung für Pneumologie, Linz, Österreich 3 Kaiser Franz Josef-Spital Wien, 3. Medizinische Abteilung – Zentrum für Onkologie und Hämatologie; LBI-ACR VIEnna & ACR-ITR VIEnna, Österreich 4(More)
Introduction This multicenter, open-label, phase II study was carried out to compare the efficacy and safety of cilengitide (EMD 121974), a selective inhibitor of the cell-surface integrins αVβ3 and αVβ5, with that of docetaxel in patients with advanced non-small-cell lung cancer (NSCLC). Methods Patients (n = 140) with advanced NSCLC who had failed(More)
8014 Background: Cilengitide (EMD 121974) is the most advanced compound in clinical development of a new class of oncology drugs, the integrin inhibitors. Integrins (heterodimeric transmembrane receptors) play key roles in cell interactions. Cilengitide selectively inhibits the cell-surface integrins αVβ3 and αVβ5 on activated endothelial cells during(More)
Malignant pleural mesothelioma is a rare malignant disease that in the majority of cases is associated with asbestos exposure. The incidence in Europe is about 20 per million inhabitants and it is increasing worldwide. Initial symptoms are shortness of breath, pleural effusion, cough, and chest pain. The typical growth pattern is along the pleural surface;(More)
Treatment of malignant pleural mesothelioma (MPM) depends on performance status of the patient, tumor stage, and histological differentiation. Chemotherapy (CHT) can be administered as first- and second-line treatment in unresectable MPM or as neoadjuvant or adjuvant treatment before or after surgery. A combination of an antifolate and platinum-based CHT is(More)
A 81-year-old man presented with massive hemoptysis and dyspnea. Results of chest radiography and computer tomography were highly suspicious for a large right-sided tumor of the bronchus with impression of the right main bronchus. Because of clinical worsening the patient was transferred to our department of pulmonology. The patient died of unappeasable(More)
Malignant pleural mesothelioma (MPM) is a rare but aggressive tumor originating from the pleural cavity with a strong link to previous asbestos exposure. In order to determine the demographics, diagnostics, therapeutic strategies, and prognosis of MPM patients in Austria, the Austrian Mesothelioma Interest Group (AMIG) was founded in 2011. In this report(More)
Ein 81-jähriger Patient wurde zunächst in einem auswärtigen Krankenhaus wegen massiver Dyspnoe und Hämoptysen stationär aufgenommen. Thoraxröntgen und Computertomographie legten den Verdacht auf eine Raumforderung mit Impression des rechten Hauptbronchus nahe. Der Patient wurde zunächst symptomatisch behandelt. Wegen einer Verschlechterung des(More)
Wedge resection for undefined pulmonary nodules can not always be performed with only minimally invasive technique. Preoperative knowledge about the exclusive videoendoscopic resectability would save operating time. We evaluated 57 Patients with indeterminate pulmonary nodules to determine whether our previously reported theses about the preoperative(More)