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OBJECTIVES This study was designed to review outcomes in relation to antithrombotic therapy management strategies for patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI) with stenting. BACKGROUND There is limited evidence on the optimal antithrombotic therapy management strategies for patients with AF who undergo(More)
PURPOSE In patients on oral anticoagulation (OAC) undergoing coronary stenting (PCI-S), procedural management and in-hospital outcome have never been specifically and prospectively investigated. Also, the contribution of early bleeding to the relevant hemorrhagic rate reported at follow-up with triple therapy of OAC, aspirin, and clopidogrel is largely(More)
  • Juan M Ruiz-Nodar, Francisco Marín, +7 authors Gregory Y H Lip
  • 2012
BACKGROUND Recent European guidelines for the management of atrial fibrillation recommend oral anticoagulation (OAC) in patients with CHA(2)DS(2)-VASc score (congestive heart failure, hypertension, age ≥75 years, diabetes, history of previous stroke, vascular disease, age 65-74 years, and sex category [female]) ≥1. The HAS-BLED score (Hypertension, Abnormal(More)
A breeding population of black-browed albatrosses has been known to exist at the Ildefonso Archipelago, Chile, for >90 years but the population has never been censused using scientifically defendable methods. To estimate population size, and examine the accuracy and practicality of various census methods, the population was censused in the 2002/2003(More)
BACKGROUND To know the prevalence, the clinical and microbiological characteristics of bacteremia episodes detected on discharged patients at the emergency unit, as well as the accordance of diagnostics and the predicting factors. PATIENTS AND METHODS We analysed the cases with bacteria detected on discharged patients during 2 years (1995-1996) in an(More)
The Diego Ramirez Islands lie 60 nautical miles southwest of Cape Horn and are the breeding site for three species of burrowing seabirds: blue petrels (Halobaena caerulea), common diving petrels (Pelecanoides urinatrix) and sooty shearwater (Puffinus griseus). Burrowing seabirds are highly vulnerable to predation by introduced vertebrate pests, and Diego(More)
OBJECTIVE To compare the efficacy and safety of dual antiplatelet therapy (DAPT) and triple therapy (TT, dual antiplatelet plus warfarin) in patients with myocardial infarction (MI) or PCI with stenting (PCI-S) who also require chronic oral anticoagulation. BACKGROUND Recommendations for the optimal antiplatelet/anticoagulant treatment regimen for(More)
BACKGROUND Most evidence regarding the efficacy and safety of the antithrombotic regimens for patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention with stent (PCI-S) derives from small, single-center, retrospective datasets. To obtain further data on this issue, we carried out the prospective, multicenter, observational(More)
BACKGROUND Intravascular thrombogenesis is influenced by a complex interplay of procoagulant, anticoagulant, fibrinolytic, endothelial damage/dysfunction and inflammatory factors. We hypothesised that abnormalities of these biological systems would contribute to coronary artery disease presenting at a young age. METHODS We performed a case-control study(More)