Jose Salgado-Borges

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Several refractive and therapeutic treatments as well as several ocular or systemic diseases might induce changes in the mechanical resistance of the cornea. Furthermore, intraocular pressure measurement, one of the most used clinical tools, is also highly dependent on this characteristic. Corneal biomechanical properties can be measured now in the clinical(More)
Purpose. To compare the characteristics of asymmetric keratoconic eyes and normal eyes by Fourier domain optical coherence tomography (OCT) corneal mapping. Methods. Retrospective corneal and epithelial thickness OCT data for 74 patients were compared in three groups of eyes: keratoconic (n = 22) and normal fellow eyes (n = 22) in patients with asymmetric(More)
Purpose. To determine whether the retinal pigment epithelium (RPE) exhibits any substantial phototoxicity and, if so, which arc the major cbromophorcs involved. M&o&. Intact human RF'E cells were isolated from the posterior poles of human and bovine eyes. Lipofoscm and melanosome granules were also isolated from human donor eyes. Action spectra of oxygen(More)
w The human wrnea is a densely innervated struchxe. However, data on nerve fiber (NF) distribution in tbe human cornea are scarce possibly due to fast post mortem degeneration. Therefore, moat descriptions on comeal innervation are based on studies in rats and rabbits. Tbe present study is focussed on the ulaastruaure of NF's in the central and peripheral(More)
Puroose: The present study investigated whether flupirtine, a non-opioid analgesic agent with some NMDA antagonistic properties in viva and in vitro, protects from ischaemic retinal injury. Methods and Results: Retinal ischaemia was induced either by transient occlusion of both common carotid arteries in the rat or by a " suction cup procedure " which(More)
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