Jose M Teixeira

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Müllerian inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications.

Jose M Teixeira, S. Maheswaran, Patricia K Donahoe
Endocrine reviews
2001

Dr. Alfred Jost pioneered the field of reproductive endocrinology with his seminal observation that two hormones produced by the testes are required for the male embryo to develop a normal internal… (More)

Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice.

Pradeep S Tanwar, Ho-Joon Lee, +4 authors Jose M Teixeira
Biology of reproduction
2009

Leiomyomas and other mesenchymally derived tumors are the most common neoplasms of the female reproductive tract. Presently, very little is known about the etiology and progression of these tumors,… (More)

Adenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium.

Pradeep S Tanwar, Lihua Zhang, Jose M Teixeira
Molecular endocrinology
2011

Sertoli cells provide the microenvironment necessary for germ cell development and spermatogenesis; disruption of Sertoli cell morphology or function can lead to germ cell aplasia, which is observed… (More)

Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN

Pradeep S Tanwar, Lihua Zhang, +5 authors Jose M Teixeira
PloS one
2011

Despite the fact that epithelial ovarian cancers are the leading cause of death from gynecological cancer, very little is known about the pathophysiology of the disease. Mutations in the WNT and PI3K… (More)

Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis.

Pradeep S Tanwar, Tomoko Kaneko-Tarui, Lihua Zhang, M. Lakshmi Prasanna Rani, Makoto Mark Taketo, Jose M Teixeira
Biology of reproduction
2010

Sertoli and germ cell interactions are essential for spermatogenesis and, thus, male fertility. Sertoli cells provide a specialized microenvironment for spermatogonial stem cells to divide, allowing… (More)

Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth.

Arno E Commandeur, Aaron K. Styer, Jose M Teixeira
Human reproduction update
2015

BACKGROUND Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle tumors of the uterus. In the USA, the lifetime risk for women developing uterine leiomyomas is estimated as up to… (More)

Human endometrial cells express elevated levels of pluripotent factors and are more amenable to reprogramming into induced pluripotent stem cells.

Joo Hyun Park, Laurence Daheron, Sibel Kantarci, Byung Seok Lee, Jose M Teixeira
Endocrinology
2011

The human endometrium is a tissue with remarkable plasticity and regenerative capacity. Additionally, endometrial cells can be retrieved using minimally invasive procedures, which makes them an ideal… (More)

Müllerian-inhibiting substance regulates androgen synthesis at the transcriptional level.

Jose M Teixeira, Eric Fynn-Thompson, Anita H. Payne, Patricia K Donahoe
Endocrinology
1999

Müllerian-inhibiting substance (MIS) is a hormone produced by Sertoli cells of the fetal testes that causes regression of the Müllerian ducts, the precursors to female reproductive tract structures… (More)

Developmental expression of a candidate müllerian inhibiting substance type II receptor.

Jose M Teixeira, Weicong He, +7 authors Patricia K Donahoe
Endocrinology
1996

We have isolated a candidate Müllerian inhibiting substance (MIS) type II receptor complementary DNA from an embryonic rat urogenital ridge library and have studied its binding to MIS, its… (More)

Deletion of tuberous sclerosis 1 in somatic cells of the murine reproductive tract causes female infertility.

Yoshihiro Tanaka, Joo Hyun Park, +4 authors Jose M Teixeira
Endocrinology
2012

Tumors develop with dysregulated activation of mammalian target of rapamycin (mTOR), the kinase activity of which is kept in an inactive state by a tumor suppressor dimer containing tuberous… (More)

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