Jose J. Castro

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An immense variety of fish may, on occasions, aggregate around or beassociated with floating structures such as drifting algae, jelliedzooplankton, whales, floats or anchored fish aggregating devices (ineffect, there are over 333 fish species belonging to 96 familiesrecorded in the literature). Several hypotheses have been advanced to explain this behaviour(More)
Polyimide regenerative electrodes (RE) constitute a promising neural interface to selectively stimulate regenerating fibers in injured nerves. The characteristics of the regeneration through an implanted RE, however, are only beginning to be established. It was recently shown that the number of myelinated fibers distal to the implant reached control values(More)
The mechanisms by which ethanol consumption causes accumulation of hepatic triacylglycerols are complex. AMP-activated protein kinase (AMPK) plays a central role in the regulation of lipid metabolism. Therefore, in the present study we investigated whether AMPK may have a role in the development of ethanol-induced fatty liver. Hepatocytes isolated from rats(More)
In the rodent trigeminal principal nucleus (Pr5) the barrelette thalamic-projecting neurons relay information from individual whiskers to corresponding contralateral thalamic barreloids. Here we investigated the presence of lateral asymmetries in the dendritic trees of these neurons, and the morphometric changes resulting from input-dependent plasticity in(More)
OBJECTIVE To address the need for nucleos(t)ide reverse transcriptase inhibitor (NRTI)-sparing regimens, we explored the virologic and pharmacokinetic characteristics of maraviroc plus ritonavir-boosted darunavir in a single-arm, open-label, 96-week study. METHODS Twenty-four antiretroviral-naive R5 HIV-1-infected participants received maraviroc 150 mg(More)
PURPOSE To determine whether the eye's optical quality is correlated to the visual discrimination capacity of patients treated with LASIK using two different ablation algorithms. METHODS Visual discrimination was evaluated by the disturbance index under low illumination (Halo v1.0 software, Laboratory of Vision Sciences and Applications) in two groups of(More)
PURPOSE To analyze the influence of higher-order aberrations on binocular visual performance under mesopic conditions. METHODS We measured aberrations in both eyes of 35 emmetropic observers with a Wasca aberrometer. Binocular visual performance was checked with both binocular summation for contrast sensitivity function and a parameter that characterizes(More)
The aim of this study is to examine the effects of aging as well as visual impairment on retinal-image quality and visual performance in drivers. We use a new visual test called Halo v1.0 software for quantifying the discrimination capacity, an important visual function for evaluating the visual disturbances perceived by the observer. The study included 55(More)
We evaluate the effect of the emmetropization technique LASIK (laser-assisted in situ keratomileusis) on stereoscopic vision. For this, we used a mirror stereoscope to measure the upper disparity limit D(max) before (with best correction) and after LASIK for 30 patients. The results show that the upper disparity limit declines from 41.1 min of arc on(More)
We were interested in analyzing the regulation by mitogen-activated protein kinases (MAPKs) of cisplatin-provoked toxicity in epithelial renal tubule cell lines, when assayed under culture conditions (cell confluence plus serum deprivation), which mimic the characteristics of a nonproliferating epithelium. Under these restrictive growth conditions,(More)