José Wálber Miranda Costa Cruz

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INTRODUCTION Supraceliac aortic clamping in major vascular procedures promotes splanchnic ischemia and reperfusion (I/R) injury that may induce endothelial dysfunction, widespread inflammation, multiorgan dysfunction, and death. We tested the hypothesis that local or remote ischemic preconditioning (IPC) may be protective against injury after supraceliac(More)
In this paper, a java-based simulator of Dynamical Systems and PID control is presented. This simulator implements linear low-order process models (first order, second order and third order), open-loop architecture and closed-loop architecture with a linear PID feedback controller. At the past, a hardware simulator (HW123b) for the three process models was(More)
In this paper, an interactive demonstration of a java-based simulator of dynamical systems is presented. This simulator implements linear low-order process models (first order, second order and third order). Open-loop control and closed-loop tests can be done with the application. The main contribution is a Java application that can be used by the(More)
We examined the effects of hypertonic saline (HS) on inflammatory, metabolic variables, and bacterial translocation (BT) in rats submitted to intestinal obstruction and ischemia (IO). Male Wistar rats were submitted to IO and treated, 2 h thereafter, with lactated Ringer's (LR) (4 mL/kg per 5 min, i.v.) or HS (7.5% NaCl, 4 mL/kg per 5 min, i.v.).(More)
In this paper, a Java stand-alone application for linear control systems simulation is presented. This simulator implements linear low-order process models (first order, second order and third order), open-loop architecture and closed-loop architecture with a linear PID feedback controller. Modeling and dynamical simulation are now basic tools for(More)
Hemorrhagic shock/reperfusion (HS/R) followed by sepsis triggers systemic microcirculatory disturbances that may induce multiple organ failure. The present study evaluated the effects of HS/R and cecal ligation and puncture, followed by necrotic cecal resection/peritoneal lavage (REL) on leukocyte-endothelium interactions at the mesentery. Eighty-one(More)
BACKGROUND Defective leukocyte-endothelial interactions are observed in experimental diabetes and may reduce the capacity to mount an adequate inflammatory response. The present study investigated the effect of ascorbic acid, an inhibitor of free radical and glycated protein formation as well as an aldose reductase inhibitor, on leukocyte-endothelial(More)
In this paper, a java-based simulator of dynamical systems and signals is presented. This simulator implements linear low-order process models. Stability analysis, open-loop control and closed-loop tests can be done with the application. Analysis of signals and noise is available using the Fast Fourier Transform (FFT). The main contribution is a Java(More)
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