José Valero

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This review is the continuation of three previously published articles [Jorrin JV, Maldonado AM, Castillejo MA. Plant proteome analysis: a 2006 update. Proteomics 2007; 7: 2947-2962; Rossignol M, Peltier JB, Mock HP, Matros A, Maldonado AM, Jorrin JV. Plant proteome analysis: a 2004-2006 update. Proteomics 2006; 6: 5529-5548; Canovas FM, Dumas-Gaudot E,(More)
Water is a natural, sometimes scarce, and fundamental resource for life, essential both for agriculture in many regions of the world and also to achieve sustainability in production systems. Maximizing net returns with the available resources is of the utmost importance, but doing so is a complex problem, owing to the many factors that affect this process(More)
The most common treatment for hydrocephalus remains the ventriculoperitoneal shunt. Yet, the most frequent complication is ventricular catheter obstruction, which may account for 50–80 % of newly inserted shunts. Although many factors contribute to this, the main one is related to flow characteristics of the catheter within the hydrocephalic brain. A(More)
Based on a landmark study by Lin et al. of the two-dimensional flow in ventricular catheters (VCs) via computational fluid dynamics (CFD), we studied in a previous paper the three-dimensional flow patterns of five commercially available VC. We found that the drainage of the cerebrospinal fluid (CSF) mostly occurs through the catheter’s most proximal holes.(More)
A previous study by computational fluid dynamics (CFD) of the three-dimensional (3-D) flow in ventricular catheters (VC) disclosed that most of the total fluid mass flows through the catheter’s most proximal holes in commercially available VC. The aim of the present study is to investigate basic flow patterns in VC prototypes. The general procedure for the(More)
We study the nonlinear dynamics of a reaction-diffusion equation where the nonlinearity presents a discontinuity. We prove the upper semicontinuity of solutions and of the global attractor with respect to smooth approximations of the nonlinear term. We also give a complete description of the set of fixed points and study their stability. Finally, we analyze(More)
BACKGROUND Hydrocephalus is a medical condition consisting of an abnormal accumulation of cerebrospinal fluid within the brain. A catheter is inserted in one of the brain ventricles and then connected to an external valve to drain the excess of cerebrospinal fluid. The main drawback of this technique is that, over time, the ventricular catheter ends up(More)